Shi J, Wang H, Hang C, Pan Y, Liu C, Zhang Z
Department of Neurosurgery, Jinling Hospital, Nanjing University, School of Medicine, People's Republic of China.
Surg Neurol. 1999 Nov;52(5):473-8; discussion 478-9. doi: 10.1016/s0090-3019(99)00123-8.
Extra-axial cavernous hemangiomas are rare and have a propensity to develop within the cavernous sinus. Total removal of these vascular tumors is difficult due to the risk of severe intraoperative bleeding and the complicated neurovascular structures of the cavernous sinus. Only a small number of cases have been reported to be successfully totally removed.
Retrospective studies were done in three cases of extraaxial cavernous hemangiomas located in the cavernous sinus. All three patients presented with clinical symptoms common to other tumors located in the region, such as headache and impairment of cranial nerve function. Their preoperative MRI results showed significant hyperintensity on T2-weighted images and marked enhancement with gadolinium-DTPA that delineated a sharp tumor margin.
All three patients underwent total tumor removal, with an uneventful postoperative course. There was no postoperative neurological deficit in one patient, and a complete ophthalmoplegia and diminished sensation in the V1 distribution in two patients. Three months after operation, follow-up MRI or CT scan showed no residual tumor.
Surgical resection of these lesions was possible but difficult because of severe bleeding. Avoiding piecemeal removal before the main feeding arteries are interrupted can minimize intraoperative bleeding.
轴外海绵状血管瘤较为罕见,且倾向于在海绵窦内发生。由于术中严重出血风险以及海绵窦复杂的神经血管结构,完全切除这些血管性肿瘤具有一定难度。仅有少数病例报道成功实现了完全切除。
对3例位于海绵窦的轴外海绵状血管瘤进行回顾性研究。所有3例患者均表现出该区域其他肿瘤常见的临床症状,如头痛和颅神经功能障碍。其术前磁共振成像(MRI)结果显示,在T2加权图像上呈明显高信号,注射钆喷替酸葡甲胺(Gd-DTPA)后有显著强化,勾勒出清晰的肿瘤边界。
所有3例患者均接受了肿瘤全切手术,术后病程平稳。1例患者术后无神经功能缺损,2例患者出现完全性眼肌麻痹以及V1分布区感觉减退。术后3个月,随访MRI或CT扫描显示无肿瘤残留。
由于严重出血,手术切除这些病变虽可行但具有难度。在阻断主要供血动脉之前避免分块切除可将术中出血降至最低。