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海绵窦血管瘤:病例系列、综述及假说

Cavernous sinus hemangiomas: a series, a review, and an hypothesis.

作者信息

Linskey M E, Sekhar L N

机构信息

Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pennsylvania.

出版信息

Neurosurgery. 1992 Jan;30(1):101-8. doi: 10.1227/00006123-199201000-00018.

DOI:10.1227/00006123-199201000-00018
PMID:1738435
Abstract

Cavernous sinus hemangiomas represent 3% of all benign cavernous sinus tumors. They are dangerous tumors because of the risk of excessive bleeding, but they are easier to dissect from surrounding structures than meningiomas because of the presence of a pseudocapsule. Three cases where total excision was achieved with minimal blood loss, without stroke, and with preservation of cranial nerve function in 2 cases are reported, and 50 cases from the literature are reviewed. Hemangiomas can be distinguished preoperatively from over one-half of meningiomas by their marked hyperintensity on T2-weighted magnetic resonance imaging. They arise within the cavernous sinus and extend laterally by dissecting between the two layers of dura lining the floor of the middle fossa. Cranial nerves III, IV, and V remained stretched over the tumor surface within the overlying dura, whereas cranial nerve VI is found within the tumor and is the most difficult cranial nerve to preserve. Principles for successful and safe excision include preoperative assessment of the safety of temporary or permanent carotid artery occlusion, obtaining early proximal carotid artery control, carefully developing the plane between the dura and the tumor pseudocapsule, early devascularization of the tumor, and avoiding "piecemeal" tumor resection. A few cases demonstrated tumor shrinkage with radiation therapy which should be considered for patients with incomplete tumor excision or who are too ill to undergo surgery.

摘要

海绵窦血管瘤占所有海绵窦良性肿瘤的3%。由于存在过度出血的风险,它们是危险的肿瘤,但由于存在假包膜,与脑膜瘤相比,它们更容易从周围结构中分离出来。报告了3例实现全切、失血极少、无卒中且2例保留颅神经功能的病例,并对文献中的50例病例进行了回顾。通过T2加权磁共振成像上的明显高信号,海绵状血管瘤在术前可与超过一半的脑膜瘤相鉴别。它们起源于海绵窦内,并通过在中颅窝底硬膜的两层之间分离而向外侧延伸。第三、第四和第五对颅神经在覆盖的硬膜内仍伸展在肿瘤表面,而第六对颅神经位于肿瘤内,是最难保留的颅神经。成功安全切除的原则包括术前评估临时或永久性颈动脉闭塞的安全性、尽早获得近端颈动脉控制、仔细分离硬膜与肿瘤假包膜之间的平面、尽早使肿瘤去血管化以及避免“碎块式”肿瘤切除。少数病例显示放射治疗后肿瘤缩小,对于肿瘤切除不完全或病情太重无法接受手术的患者应考虑采用放射治疗。

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