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[吸毒者中乙型肝炎、丙型肝炎和人类免疫缺陷病毒的感染率]

[The prevalence of infection by the hepatitis B, C and human immunodeficiency viruses in drug users].

作者信息

Jiménez Fàbrega X, Carballo Almeida A, Batalla Martínez C, Comín Bertrán E, Cuenca Oliva A M, Ezpeleta García A, López Gonzalo E, Parellada Esquius N

机构信息

ABS Dr. Pujol i Capsada, El Prat de Llobregat, Barcelona.

出版信息

Aten Primaria. 1999 Oct 15;24(6):368-71.

PMID:10596229
Abstract

OBJECTIVE

Estimate the prevalence of the hepatitis B (HBV) infection, hepatitis C (HCV) and human immunodeficiency virus (HIV) and its coexistence in intravenous drug users, in order to start afterwards a vaccination and sanitary training programmes.

PATIENTS AND METHODS

Intravenous drug users attended in a health centre and in the drugs addition deshabitation centre of reference located in a marginal urban quarter. Patients were detected from the health centre. During one year (June 1995-1996) facts were collected. The age, sex, consumption, type, administration mechanism and also the described serologies were analysed. It has been carried out descriptive statistics and applied the chi-square [correction of square-ji] test.

RESULTS

A study of 355 patients, 295 (83.1%) males and 60 (16.9%) females was carried out. The average age was 28.6 years (SD = 6.5). All serologies in 113 (31.8%) were available. The positive serologies for HIV, 64.6% for HBV and 64.4% had 71.1% for HCV. The three of them coexisted in a 35.4% between HIV, 39.1% of them were VHB and 88% VHC. 49.1% were VHB and VHC. The infection from any of the three virus was related with intravenous administration mechanism, but not with sex or drug type.

CONCLUSION

The infection caused from the virus above mentioned is frequent in drug users. A not negligible percentage of patients could benefit from the hepatitis B vaccine administration (67.6%) or other preventive measures.

摘要

目的

评估静脉吸毒者中乙型肝炎病毒(HBV)感染、丙型肝炎病毒(HCV)和人类免疫缺陷病毒(HIV)的流行情况及其共存情况,以便随后启动疫苗接种和卫生培训计划。

患者与方法

在位于城市边缘地区的一个健康中心和戒毒康复中心对静脉吸毒者进行调查。患者从健康中心检出。在一年时间里(1995年6月至1996年)收集相关情况。分析了年龄、性别、吸毒情况、类型、给药方式以及所述的血清学检查结果。进行了描述性统计并应用卡方检验。

结果

对355名患者进行了研究,其中男性295名(83.1%),女性60名(16.9%)。平均年龄为28.6岁(标准差=6.5)。113名患者(31.8%)的所有血清学检查结果均可用。HIV血清学阳性率为64.6%,HBV为64.4%,HCV为71.1%。三者同时存在的情况中,HIV、HBV和HCV分别为35.4%、39.1%和88%。49.1%为HBV和HCV同时存在。这三种病毒中任何一种的感染都与静脉给药方式有关,但与性别或毒品类型无关。

结论

上述病毒引起的感染在吸毒者中很常见。相当比例的患者(67.6%)可从接种乙肝疫苗或其他预防措施中获益。

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引用本文的文献

1
[Hepatitis C, HIV infection and delay in diagnosis].[丙型肝炎、艾滋病毒感染与诊断延误]
Aten Primaria. 2002 Dec;30(10):666; author reply 666-7. doi: 10.1016/s0212-6567(02)79135-x.