Colin J, Robinet A, Cochener B
Department of Ophthalmology, Brest University Hospital, France.
Ophthalmology. 1999 Dec;106(12):2281-4; discussion 2285. doi: 10.1016/S0161-6420(99)90526-2.
To prospectively evaluate the incidence of complications, particularly retinal detachment, 7 years after clear lens extraction (CLE) for myopia greater than -12 diopters (D).
Extended follow-up of noncomparative case series.
Fifty-two eyes of 30 patients with preoperative myopia greater than -12 D, best-corrected visual acuity (BCVA) of 20/100 or better, and intolerance of contact lenses.
Patients with lattice degeneration, retinal tear, or hole underwent photocoagulation before CLE. The authors performed phacoemulsification through a 3.2-mm-wide incision using primary irrigation and aspiration, widened the incision to 6.5 mm, and implanted a one-piece polymethyl methacrylate intraocular lens (IOL).
The BCVA, uncorrected visual acuity (UCVA), stability of spherical equivalent (SE), neodymium:YAG (Nd:YAG) capsulotomy rate, and complications (especially retinal detachment).
At 7 years, the SEs of 29 eyes (59.1%) were within +/-1.0 D of emmetropia and 42 eyes (85.7%) were within +/-2.0 D. Mean SE was -1.01 D (+/-0.94). At 7 years, mean UCVA was 20/80 compared with 20/66 at 1 year. BCVA and UCVA were better in eyes with open capsules versus intact capsules. During the 7 years, 30 eyes (61.2%) required capsulotomy for opacification. Mean time for capsulotomy was 48.4 months after CLE. The authors performed ten argon laser retinal treatments after surgery, with all but one in the first postoperative year. The overall incidence of posterior vitreous detachment was 16.3%. The incidence of retinal detachment during the 7 years was 4 of 49 eyes, or 8.1% (vs. 2.0% at 4 years). One patient had bilateral retinal detachments.
Despite advances in surgical technique, retinal detachment remains a major concern after CLE for high myopia. In the authors' series, the incidence of retinal detachment after CLE was nearly double that estimated for persons with myopia greater than -10 D who do not undergo surgery. Although CLE has advantages, including rapid and predictable visual rehabilitation, stable refraction, the ability to replace the IOL, and often superb optical quality with no irregular astigmatism, it is invasive and can result in severe vision loss. Long and continuous follow-up of the outcomes of CLE for high myopia is absolutely necessary before the authors can consider CLE as a routine option for patients with high myopia.
前瞻性评估近视度数大于-12屈光度(D)的患者行透明晶状体摘除术(CLE)7年后并发症的发生率,尤其是视网膜脱离的发生率。
非对照病例系列的长期随访。
30例术前近视度数大于-12 D、最佳矫正视力(BCVA)为20/100或更好且不耐受隐形眼镜的患者的52只眼。
有格子样变性、视网膜裂孔或视网膜洞的患者在CLE术前接受光凝治疗。作者通过3.2 mm宽的切口进行超声乳化并采用初级灌注抽吸,将切口扩大至6.5 mm,然后植入一片式聚甲基丙烯酸甲酯人工晶状体(IOL)。
BCVA、未矫正视力(UCVA)、等效球镜度(SE)的稳定性、钕:钇铝石榴石(Nd:YAG)晶状体切开术的发生率以及并发症(尤其是视网膜脱离)。
7年后,29只眼(59.1%)的SE在正视眼±1.0 D范围内,42只眼(85.7%)在±2.0 D范围内。平均SE为-1.01 D(±0.94)。7年后,平均UCVA为20/80,而1年后为20/66。开放囊袋的眼的BCVA和UCVA优于完整囊袋的眼。在这7年中,30只眼(61.2%)因晶状体混浊需要进行晶状体切开术。晶状体切开术的平均时间为CLE术后48.4个月。作者在术后进行了10次氩激光视网膜治疗,除1次外均在术后第一年。玻璃体后脱离的总发生率为16.3%。7年期间视网膜脱离的发生率为49只眼中有4只,即8.1%(4年时为2.0%)。1例患者发生双侧视网膜脱离。
尽管手术技术有所进步,但对于高度近视患者,CLE术后视网膜脱离仍然是一个主要问题。在作者的系列研究中,CLE术后视网膜脱离的发生率几乎是未接受手术的近视度数大于-10 D的患者估计发生率的两倍。尽管CLE具有一些优点,包括快速且可预测的视力恢复、屈光稳定、能够更换IOL以及通常具有出色的光学质量且无不规则散光,但它是一种侵入性手术,可能导致严重的视力丧失。在作者将CLE视为高度近视患者的常规选择之前,对高度近视患者CLE的结果进行长期持续随访绝对必要。