Georgiewa P, Rzanny R, Hopf J M, Knab R, Glauche V, Kaiser W A, Blanz B
Department of Child and Adolescent Psychiatry, Friedrich-Schiller-University of Jena, Germany.
Neuroreport. 1999 Nov 8;10(16):3459-65. doi: 10.1097/00001756-199911080-00036.
The present study addresses phonological processing in children with developmental dyslexia. Following the hypothesis of a core deficit of assembled phonology in dyslexia a set of hierarchically structured tasks was applied that specifically control for different kinds of phonological coding (assembled versus addressed phonological strategies). Seventeen developmental dyslexics and 17 normal reading children were scanned during four different tasks: (1) passive viewing of letter strings (control condition), (2) passive reading of non-words, (3) passive reading of legal words, and (4) a task requiring phonological transformation. Statistical analysis of the data was performed using statistical parametric mapping (SPM96). Comparison of patterns of activation in dyslexic and normal reading children revealed significant differences in Broca's area and the left inferior temporal region for both, non-word reading and the phonological transformation task. The present data provide new evidence for alteration of the phonological system in dyslexic children, and in particular, the system that mediates assembled phonological coding.
本研究探讨了发育性阅读障碍儿童的语音加工。根据阅读障碍中组合语音核心缺陷的假设，应用了一组层次结构任务，专门控制不同类型的语音编码（组合语音策略与定位语音策略）。在执行四项不同任务期间，对17名发育性阅读障碍儿童和17名正常阅读儿童进行了扫描：（1）被动观看字母串（对照条件），（2）被动阅读非单词，（3）被动阅读合法单词，以及（4）一项需要语音转换的任务。使用统计参数映射（SPM96）对数据进行统计分析。阅读障碍儿童和正常阅读儿童激活模式的比较显示，在非单词阅读和语音转换任务中，布洛卡区和左颞下区域均存在显著差异。目前的数据为阅读障碍儿童语音系统的改变提供了新证据，特别是介导组合语音编码的系统。
