Olofsson B, Jeltsch M, Eriksson U, Alitalo K
Ludwig Institute for Cancer Research, Box 240, Stockholm, SE-171 77, Sweden.
Curr Opin Biotechnol. 1999 Dec;10(6):528-35. doi: 10.1016/s0958-1669(99)00024-5.
Endothelial growth factors and their receptors may provide important therapeutic tools for the treatment of pathological conditions characterised by defective or aberrant angiogenesis. Vascular endothelial growth factor (VEGF) is pivotal for vasculogenesis and for angiogenesis in normal and pathological conditions. VEGF-B and VEGF-C provide this gene family with additional functions, for example, VEGF-C also regulates lymphangiogenesis.
内皮生长因子及其受体可能为治疗以血管生成缺陷或异常为特征的病理状况提供重要的治疗工具。血管内皮生长因子（VEGF）在正常和病理状况下对于血管发生和血管生成均至关重要。VEGF - B和VEGF - C为该基因家族赋予了其他功能，例如，VEGF - C还调节淋巴管生成。
