Kang J K, Lee I W
Department of Neurosurgery, Kangnam St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Seoul, Korea.
Childs Nerv Syst. 1999 Nov;15(11-12):711-7. doi: 10.1007/s003810050460.
Ventricular CSF shunting surgery has changed the overall outcome figures for hydrocephalic patients over the past three decades. The factors that have improved the outcome are evolution of the shunt systems, improvement of the surgical environment and use of potent antibiotics, technological advances in brain imaging, and refinements in the assessment of cognitive and functional outcomes and of actuarial statistical techniques. But the recent large studies revealed that nearly half of all shunt placements were for revision, and there is a low but real percentage of cases in which death and neurological impairment are related to shunt surgery. The most frequent complication was shunt obstruction, followed by infection, disconnection, hematoma and slit ventricle syndrome. This clearly means that the shunt systems and the techniques in current use involve many problems that have yet to be solved. To solve these problems, new shunt systems should be developed and continuous efforts at reducing shunt infection should be made. The overall complication rate in the authors' series was 31.7%, but we have been able to reduce the complication rate from 37% to 25% by exercising special care focused on the surgical environment and techniques. Careful, long-term follow-up using various parameters and proper statistical analysis is another important factor in improving surgical outcome. Multicenter and international studies will be easier with the development of a network, and it will give us a strong background to treat hydrocephalus.
在过去三十年中,脑室脑脊液分流手术改变了脑积水患者的总体预后数据。改善预后的因素包括分流系统的发展、手术环境的改善和强效抗生素的使用、脑成像技术的进步,以及认知和功能预后评估及精算统计技术的完善。但最近的大型研究表明,几乎一半的分流手术是为了修复,并且有一小部分但确实存在的病例中,死亡和神经功能损害与分流手术有关。最常见的并发症是分流梗阻,其次是感染、断开、血肿和裂隙脑室综合征。这清楚地表明,目前使用的分流系统和技术存在许多有待解决的问题。为了解决这些问题,应开发新的分流系统,并持续努力降低分流感染率。作者系列中的总体并发症发生率为31.7%,但通过对手术环境和技术给予特别关注,我们已能够将并发症发生率从37%降至25%。使用各种参数进行仔细的长期随访和适当的统计分析是改善手术预后的另一个重要因素。随着网络的发展,多中心和国际研究将变得更加容易,这将为我们治疗脑积水提供有力支持。