Jouppila P, Kauppila A, Koivisto M, Moilanen I, Ylikorkala O
Acta Obstet Gynecol Scand Suppl. 1975;44:13-9. doi: 10.3109/00016347509156425.
In a series of 335 twin patients delivered over 1965-1973, active management was promoted during the pregnancy and delivery. The twin diagnosis was made in the 33.7th gestational week on an average. The diagnosis was made prior to delivery in 83.0 % of the cases, and during 1971-1973 the diagnosis was made before the 32nd week of pregnancy in 40.2 % of the cases. The perinatal mortality (PNM) rates were highly significantly (p less than 0.001) lower, the birthweights of A and B higher (p less than 0.001), and the number of gestational weeks at delivery greater (p less than 0.001) in the group diagnosed during pregnancy than in the group in which the twins were not diagnosed until at delivery. 56.4 % of the patients stayed in hospital for more than 2 days during the pregnancy and 34.9 % for over 10 days. The average period of hospitalization was 11.3 days. The perinatal mortality (PNM) of both the A and the B infants was lowest in the group hospitalized for over 10 days. In the group which had stayed in hospital for over 10 days the mean birthweight of the A infants was higher by 100 g and that of the B infants by 94 g than in the group not hospitalized despite the early diagnosis of twins. The average duration of delivery was 9.3 hours. Active efforts were made to shorten the interval between the births of the two infants, and it was 17.5 minutes on an average. This interval was not, however, related to the PNM rate of the B twins. On the basis of our findings, we wish to emphasize particularly the importance of the early diagnosis of twins.
在1965年至1973年间分娩的335对双胞胎患者中，在孕期和分娩期间推行了积极管理措施。双胞胎的诊断平均在孕33.7周时做出。83.0%的病例在分娩前做出诊断，在1971年至1973年期间，40.2%的病例在孕32周前做出诊断。与分娩时才诊断出双胞胎的组相比，孕期诊断出双胞胎的组围产期死亡率（PNM）显著更低（p<0.001），A、B胎儿出生体重更高（p<0.001），分娩时孕周数更多（p<0.001）。56.4%的患者孕期住院超过2天，34.9%的患者住院超过10天。平均住院时间为11.3天。A、B两组婴儿的围产期死亡率在住院超过10天的组中最低。在住院超过10天的组中，A胎儿的平均出生体重比未住院但早期诊断出双胞胎的组高100克，B胎儿高94克。平均分娩时长为9.3小时。积极努力缩短两个婴儿出生的间隔时间，平均间隔时间为17.5分钟。然而，这一间隔时间与B组双胞胎的围产期死亡率无关。基于我们的研究结果，我们特别想强调双胞胎早期诊断的重要性。
