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肝硬化中的细菌感染

Bacterial infections in liver cirrhosis.

作者信息

Navasa M, Fernández J, Rodés J

机构信息

Liver Unit, IMD, Hospital Clínic, IDIBAPS, University of Barcelona, Spain.

出版信息

Ital J Gastroenterol Hepatol. 1999 Oct;31(7):616-25.

Abstract

The incidence of bacterial infections in cirrhotic patients admitted to hospital is very high. In several studies, 30% to 50% of cirrhotics presented bacterial infections at admission, or developed this type of complication during hospitalization. Most bacterial infections in cirrhotic patients are hospital-acquired. Between 15% to 35% of cirrhotics admitted to hospital develop nosocomial infections; these figures contrast sharply with the hospital-acquired infection rate in the general hospital population (5% to 7%). Urinary tract infections (12% to 29%), spontaneous bacterial peritonitis (7% to 23%), respiratory tract infections (6% to 10%) and bacteraemia (4% to 9%) are the most frequent bacterial infectious complications seen in cirrhotic patients. However, since spontaneous bacterial peritonitis is the most characteristic bacterial infection in cirrhosis, this report will focus (mainly) on this infectious complication.

摘要

肝硬化患者入院时细菌感染的发生率非常高。在多项研究中,30%至50%的肝硬化患者在入院时出现细菌感染,或在住院期间发生此类并发症。肝硬化患者的大多数细菌感染是医院获得性的。入院的肝硬化患者中有15%至35%发生医院感染;这些数字与普通医院人群的医院获得性感染率(5%至7%)形成鲜明对比。尿路感染(12%至29%)、自发性细菌性腹膜炎(7%至23%)、呼吸道感染(6%至10%)和菌血症(4%至9%)是肝硬化患者中最常见的细菌感染并发症。然而,由于自发性细菌性腹膜炎是肝硬化最具特征性的细菌感染,本报告将(主要)聚焦于这种感染性并发症。

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