Rostkowska-Nadolska B, Pośpiech L, Bochnia M
Department of Otolaryngology, University Medical School, Wrocław, Poland.
Arch Immunol Ther Exp (Warsz). 1999;47(5):321-5.
An examination of the content of arsenic, nickel, copper, selenium, zinc, and iron in the serum of 78 patients with carcinoma of the larynx was carried out. The patients were divided into 4 groups: I - patients before treatment, II - patients after surgical treatment, III - patients after radiotherapy, IV - patients after combined treatment (surgery treatment + radiotherapy). The control group was formed of 17 patients operated for deviation of the nasal septum. Higher concentrations of arsenic, nickel and copper were found in the serum of the patients with carcinoma of the larynx before treatment (group I) as compared with the control group, whereas the concentrations of selenium, zinc and iron were lower. In the groups of patients after treatment, the highest concentrations of iron and zinc were found after surgical treatment. The level of selenium in all groups of patients was considerably lower than in the control group.
对78例喉癌患者血清中的砷、镍、铜、硒、锌和铁含量进行了检测。患者分为4组：I组——治疗前患者；II组——手术治疗后患者；III组——放疗后患者；IV组——综合治疗（手术治疗+放疗）后患者。对照组由17例因鼻中隔偏曲而接受手术的患者组成。与对照组相比，治疗前喉癌患者（I组）血清中的砷、镍和铜浓度较高，而硒、锌和铁的浓度较低。在治疗后的患者组中，手术治疗后铁和锌的浓度最高。所有患者组中的硒水平均显著低于对照组。
