真菌苯并查耳酮类化合物的结构解析，小鼠巨噬细胞中脂滴形成的新型抑制剂
Structure elucidation of fungal phenochalasins, novel inhibitors of lipid droplet formation in mouse macrophages.
作者信息
Tomoda H, Namatame I, Tabata N, Kawaguchi K, Si S, Omura S
机构信息
Graduate School of Pharmaceutical Sciences, Kitasato University, Japan.
出版信息
J Antibiot (Tokyo). 1999 Oct;52(10):857-61. doi: 10.7164/antibiotics.52.857.
PMID:10604754
Abstract
The structures of phenochalasins A and B were elucidated by spectroscopic studies including various NMR measurements. Phenochalasins A and B have the cytochalasan skeleton of the 21,23-dioxa, 17,22-dione moiety containing unique phenyl and O-methyl phenyl residues at the C-10 position, respectively.
摘要
通过包括各种核磁共振测量在内的光谱研究阐明了苯杯伞素A和B的结构。苯杯伞素A和B具有细胞松弛素骨架，其21,23 - 二氧杂、17,22 - 二酮部分在C - 10位分别含有独特的苯基和O - 甲基苯基残基。
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