Sleijfer D T, van der Werf T S, de Mulder P H
Afd. Medische Oncologie, Academisch Ziekenhuis, Groningen.
Ned Tijdschr Geneeskd. 1999 Nov 27;143(48):2421-4.
Dyspnoea is a frequent symptom in advanced cancer patients. The control of breathing can be impaired by different mental and physical factors that may coincide and change over time. Apart from the treatment of specific pathophysiologic causes, symptomatic management is of utmost importance. Only few controlled trials evaluating the efficacy of symptomatic treatment of dyspnoea in advanced cancer patients are available. There is evidence that systemically administered opioids are effective in alleviating breathlessness in patients with cancer.
呼吸困难是晚期癌症患者的常见症状。呼吸控制可能会受到不同的心理和生理因素影响,这些因素可能同时存在并随时间变化。除了治疗特定的病理生理原因外,对症治疗至关重要。目前仅有少数对照试验评估晚期癌症患者呼吸困难对症治疗的疗效。有证据表明,全身使用阿片类药物可有效缓解癌症患者的呼吸急促。