鸭嘴花提取物对动物机械或化学刺激诱发咳嗽的镇咳作用。
Antitussive effect of Adhatoda vasica extract on mechanical or chemical stimulation-induced coughing in animals.
作者信息
Dhuley J N
机构信息
Department of Pharmacology and Toxicology, Hindustan Antibiotics Ltd., Pimpri, Pune, India.
出版信息
J Ethnopharmacol. 1999 Nov 30;67(3):361-5. doi: 10.1016/s0378-8741(99)00074-4.
The antitussive activity of Adhatoda vasica (AV) extract was evaluated in anaesthetized guinea pigs and rabbits and in unanaesthetized guinea pigs. AV was shown to have a good antitussive activity. Intravenously, it was 1/20-1/40 as active as codeine on mechanically and electrically induced coughing in rabbits and guinea-pigs. After oral administration to the guinea-pig the antitussive activity of AV was similar to codeine against coughing induced by irritant aerosols.
在麻醉的豚鼠和兔子以及未麻醉的豚鼠身上评估了鸭嘴花提取物的镇咳活性。结果表明，鸭嘴花具有良好的镇咳活性。静脉注射时，在兔子和豚鼠身上，其对机械性和电诱导咳嗽的活性是可待因的1/20 - 1/40。给豚鼠口服后，鸭嘴花对刺激性气雾剂诱导咳嗽的镇咳活性与可待因相似。
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