Khandelwal Poonam, Wadhwani Barkha Darra, Rao Ravindra Singh, Mali Deepak, Vyas Pooja, Kumar Tarun, Nair Rashmy
Department of Chemistry, Mohanlal Sukhadia University, Udaipur, 313001, Rajasthan, India.
Department of Chemistry, S.S. Jain Subodh P.G. College, Jaipur, 302004, Rajasthan, India.
Heliyon. 2024 Feb 8;10(4):e25727. doi: 10.1016/j.heliyon.2024.e25727. eCollection 2024 Feb 29.
is one of the biggest and complex genera of the Acanthaceae family. is commonly known as 'Adosa'. It is an ayurvedic medicine with a medicinal history of more than a thousand years in India. Traditionally, it is used to treat cough, asthma, phlegm, bleeding hemorrhoids, for both adults and youth. This plant possesses antiarthritis, antiseptic, antimicrobial, anti-tuberculosis, anti-inflammatory and abortifacient properties. Alkaloids are the major phytoconstituents present in the plant in the form of pyrrolo-quinazoline derivatives vasicine, vasicinone, vasicinol, adhatodine, adhatodinine, adhavasinone and anisotine etc. The asserted objectives are to conduct a systematic review on the phytochemistry, pharmacology and traditional uses of , as well as highlighting the challenges found in the research. This will promote the utilization of at extract level and further development of new drug leads based on the compounds isolated and used for treatment of various ailments. The present review covers the literature survey from 1888 to 2023. The relevant data has been collected from various peer-reviwed journals, and books Sci-Finder, PubMed, Science Direct, Google Scholar, EBSCO, online electronic journals, SpringerLink and Wiley. This paper aims to present a systematic review of known traditional applications, pharmacological and chemical aspects in .
是爵床科最大且最复杂的属之一。通常被称为“Adosa”。它是一种阿育吠陀药物，在印度有超过一千年的药用历史。传统上，它用于治疗咳嗽、哮喘、痰液、出血性痔疮，适用于成人和青少年。这种植物具有抗关节炎、防腐、抗菌、抗结核、抗炎和堕胎特性。生物碱是该植物中的主要植物成分，以吡咯并喹唑啉衍生物的形式存在，如鸭嘴花碱、去甲鸭嘴花碱、鸭嘴花醇、鸭嘴花定碱、去甲鸭嘴花定碱、鸭嘴花新酮和山梗菜碱等。本文的既定目标是对该植物的植物化学、药理学和传统用途进行系统综述，并突出研究中发现的挑战。这将促进该植物提取物水平的利用，并基于分离出的化合物进一步开发新的药物先导物，用于治疗各种疾病。本综述涵盖了1888年至2023年的文献调查。相关数据已从各种同行评审期刊、书籍以及Sci-Finder、PubMed、Science Direct、Google Scholar、EBSCO、在线电子期刊、SpringerLink和Wiley收集。本文旨在对该植物已知的传统应用、药理学和化学方面进行系统综述。
