Mahy G E, Mallett R, Leff J, Bhugra D
School of Clinical Medicine and Research, University of the West Indies, Queen Elizabeth Hospital, St Michael, Barbados.
Br J Psychiatry. 1999 Jul;175:28-33. doi: 10.1192/bjp.175.1.28.
The incidence rate for broad schizophrenia among second-generation African-Caribbean people in the United Kingdom has been reported as high. Ethnicity, migration and psychosocial stressors have been suggested as causal factors.
To determine the incidence of schizophrenia for the whole population of Barbados using an identical methodology to two previous studies in Trinidad (Bhugra et al, 1996) and London (Bhugra et al, 1997).
A 12-month study of all persons in the 18-54-year age group presenting with a psychosis for the first time was carried out on the population of Barbados. Information was collected using World Health Organization screening and measurement instruments.
On an island of just over a quarter of a million, 40 out of the 53 patients that met the inclusion criteria were categorised as S+ (narrow) schizophrenia, giving an incidence rate of 2.8/10,000 (95% CI 1.97-3.7). The incidence rate for broad schizophrenia was calculated at 3.2/10,000 (95% CI 2.3-4.1), which is significantly lower than the comparable rate for London's African-Caribbeans of 6.6/10,000 (95% CI 4.5-8.7).
The very high rate for broad schizophrenia among African-Caribbean people in the UK is probably due to environmental factors.
据报道,在英国的第二代非洲裔加勒比人中,广泛型精神分裂症的发病率很高。种族、移民和心理社会压力因素被认为是致病因素。
采用与之前在特立尼达(布格拉等人,1996年)和伦敦(布格拉等人,1997年)进行的两项研究相同的方法,确定巴巴多斯全体人口中精神分裂症的发病率。
对巴巴多斯18至54岁首次出现精神病症状的所有人进行了为期12个月的研究。使用世界卫生组织的筛查和测量工具收集信息。
在一个人口略超过25万的岛屿上,53名符合纳入标准的患者中有40名被归类为S+(狭义)精神分裂症,发病率为2.8/10000(95%可信区间1.97 - 3.7)。广泛型精神分裂症的发病率经计算为3.2/10000(95%可信区间2.3 - 4.1),这显著低于伦敦非洲裔加勒比人的可比发病率6.6/10000(95%可信区间4.5 - 8.7)。
英国非洲裔加勒比人中广泛型精神分裂症的极高发病率可能归因于环境因素。