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特立尼达精神分裂症的首次接触发病率及一年随访情况。

First-contact incidence rates of schizophrenia in Trinidad and one-year follow-up.

作者信息

Bhugra D, Hilwig M, Hossein B, Marceau H, Neehall J, Leff J, Mallett R, Der G

机构信息

Institute of Psychiatry, De Crespigny Park, London.

出版信息

Br J Psychiatry. 1996 Nov;169(5):587-92. doi: 10.1192/bjp.169.5.587.

DOI:10.1192/bjp.169.5.587
PMID:8932887
Abstract

BACKGROUND

Incidence rates of schizophrenia among UK African-Caribbeans have been reported as high. Various explanations including selective migration and genetic vulnerability have been proposed.

METHOD

In one calendar year, all new cases of psychosis presenting to various psychiatric services in two clearly defined geographical catchment areas in Trinidad-one in the rural south and the other an urban area-were studied. Standardised diagnostic instruments were applied and information collected using WHO screening and measurement instruments.

RESULTS

A total of 56 cases were collected, giving an incidence rate of 2.2/1000 of broad schizophrenia with a rate of 1.6 for S+ schizophrenia.

CONCLUSION

These rates are similar to those from the WHO study in Honolulu and Aarhus, and much lower than the rates for African-Caribbeans in London. The cases were followed up for one year and the poor outcome rate for schizophrenia was 19%. The findings are discussed in a cross-cultural context and suggestions for future research made.

摘要

背景

据报道,英国非裔加勒比人中精神分裂症的发病率很高。已经提出了各种解释,包括选择性移民和遗传易感性。

方法

在一个日历年中,对特立尼达两个明确界定的地理区域(一个在南部农村,另一个在城市地区)的各种精神科服务机构收治的所有新发精神病病例进行了研究。使用标准化诊断工具,并使用世界卫生组织的筛查和测量工具收集信息。

结果

共收集到56例病例,广泛型精神分裂症的发病率为2.2/1000,单纯型精神分裂症的发病率为1.6。

结论

这些发病率与世界卫生组织在檀香山和奥胡斯的研究结果相似,远低于伦敦非裔加勒比人的发病率。对这些病例进行了一年的随访,精神分裂症的不良结局率为19%。研究结果在跨文化背景下进行了讨论,并对未来的研究提出了建议。

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