Walker C, Wadd N J, Lucraft H H
Northern Centre for Cancer Treatment, Newcastle General Hospital, Newcastle Upon Tyne, UK.
Br J Radiol. 1999 Aug;72(860):787-91. doi: 10.1259/bjr.72.860.10624345.
A novel treatment for two patients with mycosis fungoides involving all or most of the skin surface of the head is described using large overlapping low energy electron beams. Shielding of previously treated and uninvolved areas was achieved by encapsulating cerrobend within a thermoplastic shell in one patient. In the other patient, GE Saturnes unique asymmetric electron field definition facility was used. Satisfactory dose uniformity was demonstrated by the computation of dose distributions on the full summed electron pencil beam model on the Target Series 2 treatment planning system. Verification of the calculated dose homogeneity was confirmed with lithium fluoride (TLD-100) thermoluminescent dosimetry. The relatively simple treatment set-up was accomplished easily on a routine basis and was well tolerated by the patients, both of whom have been in complete remission since their treatment.
描述了一种使用大重叠低能电子束治疗两名蕈样肉芽肿累及头部全部或大部分皮肤表面患者的新方法。在一名患者中,通过将铈铍合金封装在热塑性外壳中来实现对先前治疗区域和未受累区域的屏蔽。在另一名患者中,使用了GE Saturnes独特的不对称电子场定义设备。通过在Target Series 2治疗计划系统上的全总和电子笔形束模型上计算剂量分布,证明了令人满意的剂量均匀性。用氟化锂(TLD - 100)热释光剂量测定法证实了计算出的剂量均匀性。相对简单的治疗设置在常规基础上很容易完成,并且患者耐受性良好,两名患者自治疗后均处于完全缓解状态。