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孕早期的铁吸收——一项关于孕早期非血红素铁和亚铁吸收情况的研究。

Iron absorption in early pregnancy - a study of the absorption of non-haeme iron and ferrous iron in early pregnancy.

作者信息

Svanberg B

出版信息

Acta Obstet Gynecol Scand Suppl. 1975;48:69-85. doi: 10.3109/00016347509156331.

DOI:10.3109/00016347509156331
PMID:1062909
Abstract

The absorption of non-haeme iron in the food and from a 3 mg reference dose of ferrous iron in solution was measured in 17 healthy women before the 12th week of gestation and in 13 of the women two months after legal abortion. The absorption of ferrous iron in solution was calculated from determinations of the 55Fe activity in blood samples. The food iron absorption was measured from 59Fe-labelled test meals using a highly sensitive whole-body counter. In addition bone-marrow smears and other haematological parameters were studied. The median value of the absorption from the non-haeme food iron was 2.5% and from the ferrous iron salt 10.0 % in early pregnancy in women with storage iron. Two months after abortion the absorption increased to 12.6 and 42.6 % respectively. In early pregnancy the absorption of iron was higher in women without stainable iron in bone-marrow smears. The present results confirm previous observations that the absorption of food iron in early pregnancy is lower than the basal daily requirements. The low absorption is only partly explained by the reduced requirements of iron in early pregnancy. Some other factors related to pregnancy seem also to be involved.

摘要

对17名处于妊娠12周前的健康女性以及其中13名在合法堕胎两个月后的女性,测量了她们对食物中非血红素铁的吸收情况以及对3毫克参考剂量溶液中亚铁的吸收情况。溶液中亚铁的吸收是通过测定血样中的55Fe活性来计算的。食物中铁的吸收是使用高灵敏度全身计数器,通过对59Fe标记的试验餐进行测量的。此外,还研究了骨髓涂片和其他血液学参数。在有储存铁的女性中,妊娠早期非血红素食物铁的吸收中值为2.5%,亚铁盐的吸收中值为10.0%。堕胎两个月后,吸收分别增加到12.6%和42.6%。在妊娠早期,骨髓涂片无可染色铁的女性中铁的吸收更高。目前的结果证实了之前的观察,即妊娠早期食物铁的吸收低于每日基础需求量。吸收低只是部分地由妊娠早期对铁需求的减少所解释。一些与妊娠相关的其他因素似乎也有影响。

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