Nicol K K, Iskandar S S
Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1072, USA.
Arch Pathol Lab Med. 2000 Jan;124(1):157-9. doi: 10.5858/2000-124-0157-LCOTBM.
The oral cavity is a rare site of metastatic lesions; however, metastatic breast carcinoma must be included in the differential diagnosis of tumors of that site in women. We describe a 54-year-old woman who presented with a lesion of the floor of the mouth that histologically resembled polymorphous low-grade adenocarcinoma of the minor salivary glands, which was eventually established to represent metastatic lobular breast carcinoma. The final diagnosis was based on comparison with a primary tumor resected 13 years earlier and immunohistochemical reactivity with antibodies to steroid receptors. Relevant aspects of lobular breast carcinoma, polymorphous low-grade adenocarcinoma, and metastatic oral cavity lesions are discussed.
口腔是转移瘤的罕见发生部位；然而，转移性乳腺癌必须纳入女性该部位肿瘤的鉴别诊断中。我们报告一例54岁女性，其口底出现一个病变，组织学上类似于小涎腺多形性低度腺癌，最终确诊为转移性小叶乳腺癌。最终诊断基于与13年前切除的原发性肿瘤进行比较以及对类固醇受体抗体的免疫组化反应。本文讨论了小叶乳腺癌、多形性低度腺癌和口腔转移性病变的相关方面。
