Penland R L, Boniuk M, Wilhelmus K R
Sid W. Richardson Ocular Microbiology Laboratory, Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, USA.
Cornea. 2000 Jan;19(1):26-9. doi: 10.1097/00003226-200001000-00006.
To describe the epidemiology of Vibrio eye infections.
We reviewed the records of a patient from our institution with V. vulnificus keratitis and conducted a literature search for other cases of ocular infections with Vibrio species.
A 39-year-old fisherman was struck in his left eye with an oyster shell fragment, developed suppurative V. vulnificus keratitis, and was successfully treated with combined cefazolin and gentamicin. Including our patient, 17 cases of eye infections with Vibrio spp. have been reported, and 11 (65%) involved exposure to seawater or shellfish. Of the seven cases due to V. vulnificus (six keratitis and one endophthalmitis), six had known exposure to shellfish or seawater along the U.S. coast of the Gulf of Mexico. Of five cases of V. alginolyticus conjunctivitis, three had been exposed to fish or shellfish. Three infections with V. parahaemolyticus (one keratitis and two endophthalmitis) were reported; two of these occurred in people exposed to brackish water on or near the Gulf Coast. Two cases of postsurgical endophthalmitis, one with V. albensis and one with V. fluvialis, also were reported.
In addition to septicemia, gastroenteritis, and wound infections, halophilic noncholera Vibrio species can cause sight-threatening ocular infections. Ocular trauma by shellfish from contaminated water is the most common risk factor for Vibrio conjunctivitis and keratitis. Nearly one half of reported Vibrio infections of the eye occurred along the U.S. coast of the Gulf of Mexico.
描述弧菌性眼部感染的流行病学特征。
我们回顾了本机构一名患有创伤弧菌性角膜炎患者的病历，并对其他弧菌属眼部感染病例进行了文献检索。
一名39岁的渔民左眼被牡蛎壳碎片击中，患上了化脓性创伤弧菌性角膜炎，联合使用头孢唑林和庆大霉素治疗成功。包括我们的患者在内，已报告了17例弧菌属眼部感染病例，其中11例（65%）与接触海水或贝类有关。在7例由创伤弧菌引起的感染（6例角膜炎和1例眼内炎）中，6例已知有接触墨西哥湾美国海岸贝类或海水的经历。在5例溶藻弧菌性结膜炎病例中，3例曾接触过鱼类或贝类。报告了3例副溶血性弧菌感染（1例角膜炎和2例眼内炎）；其中2例发生在墨西哥湾沿岸或附近接触微咸水的人群中。还报告了2例术后眼内炎病例，1例由阿尔贝弧菌引起，1例由河流弧菌引起。
除败血症、肠胃炎和伤口感染外，嗜盐非霍乱弧菌可导致威胁视力的眼部感染。来自受污染水域的贝类造成的眼外伤是弧菌性结膜炎和角膜炎最常见的危险因素。报告的眼部弧菌感染病例中近一半发生在美国墨西哥湾沿岸。
