Castelino A M, Rao S K, Biswas J, Gopal L, Madhavan H N, Kumar S K
Sankara Nethralaya, Medical Research Foundation, Chennai, Tamil Nadu, India.
Cornea. 2000 Jan;19(1):30-3. doi: 10.1097/00003226-200001000-00007.
Although conjunctival rhinosporidiosis is endemic in India, associated scleral melting and staphyloma formation are quite rare. We report clinical features and management in three patients with this unusual presentation.
Retrospective review of case records of three patients with conjunctival rhinosporidiosis.
Infection occurred in young, healthy adults and was localized to the forniceal conjunctiva in all patients. The affected conjunctiva had numerous grey-white spherules, but a polyp-like lesion was not present in any patient. Diagnosis was based on clinical features and examination of scrapings from the involved conjunctiva. Treatment was surgical, with excision of infected conjunctival tissues and staphyloma repair with homologous sclera or autogenous periosteum. Failure to recognize the conjunctival pathology in one patient resulted in recurrence of the staphyloma.
Conjunctival rhinosporidiosis can be associated with scleral staphyloma in young, healthy, adults. Differentiating this entity from idiopathic scleral ectasia requires knowledge of the clinical features of conjunctival rhinosporidiosis and a high index of clinical suspicion.
尽管结膜鼻孢子虫病在印度为地方病，但相关的巩膜溶解和葡萄肿形成相当罕见。我们报告3例有这种不寻常表现患者的临床特征及治疗情况。
对3例结膜鼻孢子虫病患者的病例记录进行回顾性分析。
感染发生在年轻健康成年人中，所有患者均局限于穹窿部结膜。受累结膜有大量灰白色小球，但所有患者均无息肉样病变。诊断基于临床特征及对受累结膜刮片的检查。治疗采用手术，切除感染的结膜组织并用同种异体巩膜或自体骨膜修复葡萄肿。1例患者未认识到结膜病变导致葡萄肿复发。
结膜鼻孢子虫病可在年轻健康成年人中并发巩膜葡萄肿。将此疾病与特发性巩膜扩张相鉴别需要了解结膜鼻孢子虫病的临床特征及高度的临床怀疑指数。
