Narnoli Prasansha, Rath Suryasnata, Mohapatra Samir, Jain Mukesh, Tripathy Devjyoti
Ophthalmic Plastics, Orbit and Ocular Oncology Services, LV Prasad Eye Institute, MTC Campus, Bhubaneswar, Odisha, India.
Vitreoretina Services, Anant Bajaj Retina Institute, LV Prasad Eye Institute, MTC Campus, Bhubaneswar, Odisha, India.
Indian J Ophthalmol. 2025 Jun 1;73(Suppl 3):S389-S393. doi: 10.4103/IJO.IJO_52_24. Epub 2025 Apr 17.
To report the clinical spectrum of bulbar conjunctival rhinosporidiosis at a tertiary eye care oculoplastics facility.
Retrospective chart review of biopsy-proven ocular and adnexal rhinosporidiosis over a five-year period (2017-2022). Demographic details, clinical presentation, management interventions, and outcomes in a series of cases with bulbar conjunctival rhinosporidiosis were documented and analyzed.
A total of 14 cases of biopsy-proven bulbar conjunctival rhinosporidiosis were included in this study. These formed 22.2% of all cases of ocular adnexal rhinosporidiosis and 46.7% of all conjunctival cases diagnosed within the study period. All the cases underwent surgical excision of the conjunctival mass with five (35.7%) requiring a scleral patch graft for scleral thinning with or without staphyloma formation. Most patients had a good outcome on medium to long-term follow-up.
Even though tarsal conjunctival involvement is reported as the most common form of conjunctival rhinosporidiosis in the literature, in our series, bulbar conjunctival disease comprised nearly half of all conjunctival cases, and over 20% of all adnexal cases. Most appear to do well with complete surgical excision of the granuloma. Rarely, long-standing cases may develop scleral thinning with or without staphyloma formation which may need major tectonic support to protect the integrity of the eyeball. Most of these also appear to do well on medium to long-term follow-up.
报告在一家三级眼保健眼整形机构中球结膜鼻孢子虫病的临床特征。
对五年期间（2017 - 2022年）经活检证实的眼部和附属器鼻孢子虫病进行回顾性病历审查。记录并分析了一系列球结膜鼻孢子虫病病例的人口统计学细节、临床表现、治疗干预措施及结果。
本研究共纳入14例经活检证实的球结膜鼻孢子虫病病例。这些病例占眼部附属器鼻孢子虫病所有病例的22.2%，占研究期间诊断的所有结膜病例的46.7%。所有病例均接受了结膜肿物的手术切除，其中5例（35.7%）因巩膜变薄伴或不伴有葡萄肿形成而需要进行巩膜补片移植。大多数患者在中长期随访中预后良好。
尽管文献报道睑结膜受累是结膜鼻孢子虫病最常见的形式，但在我们的系列病例中，球结膜疾病占所有结膜病例的近一半，占所有附属器病例的20%以上。大多数病例通过肉芽肿的完全手术切除似乎预后良好。极少数情况下，长期病例可能会出现巩膜变薄伴或不伴有葡萄肿形成，这可能需要主要的结构性支持来保护眼球的完整性。大多数此类病例在中长期随访中似乎也预后良好。
