Kim H Y, Lee S Y, Kang S J, Kim H J
Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea.
Acta Ophthalmol Scand. 1999 Dec;77(6):704-8. doi: 10.1034/j.1600-0420.1999.770621.x.
The authors report three cases with solitary fibrous tumor (SFT) of the orbit with variable clinical presentation.
The authors identified three patients with a diagnosis of SFT, and clinical histories, radiographs and pathologic specimens were reviewed.
Two SFTs are reported arising in the lacrimal gland fossa of a 24-year-old male and a 26-year-old female and a retrobulbar SFT is reported occurring in a 40-year-old female. While two patients had slow growth histories, one patient had a history of rapid progression. Immunohistochemically, the tumor cells were strongly positive for CD34 in all three cases.
The clinical presentation of the orbital SFT may be varied. Immunohistochemical analysis may help in the diagnosis of solitary fibrous tumor and the treatment is en bloc excision. A careful follow-up is necessary because it may recur years after excision of the primary tumor.
作者报告三例眼眶孤立性纤维瘤(SFT),临床表现各异。
作者确定了三例诊断为SFT的患者,并回顾了其临床病史、影像学检查和病理标本。
报告了两例SFT分别发生于一名24岁男性和一名26岁女性的泪腺窝,以及一例发生于一名40岁女性的球后SFT。两名患者肿瘤生长缓慢,一名患者有快速进展史。免疫组化方面,三例肿瘤细胞CD34均呈强阳性。
眼眶SFT的临床表现可能多样。免疫组化分析有助于孤立性纤维瘤的诊断,治疗方法为整块切除。由于原发性肿瘤切除后数年可能复发,因此需要密切随访。