Ing E B, Kennerdell J S, Olson P R, Ogino S, Rothfus W E
Macomb Eye Center-Southern Illinois University 61455, USA.
Ophthalmic Plast Reconstr Surg. 1998 Jan;14(1):57-61. doi: 10.1097/00002341-199801000-00012.
Solitary fibrous tumor (SFT) of the orbit is a very rare lesion that may be misdiagnosed as fibrous histiocytoma, hemangiopericytoma, or other orbital tumors. We present a 62-year-old man who presented with painless proptosis, 20 years following left eye enucleation for a presumed neurofibroma. On T2-weighted magnetic resonance imaging (MRI), a hypointense tumor almost filled his entire left orbit. There was no intracranial extension. The specimen obtained at orbital exenteration was consistent with the histologic, immunohistochemical, and electron microscopic findings of SFT. The tumor was positive for vimentin and CD34 staining but negative for S-100 protein and epithelial membrane antigen. Only nine other cases of SFT of the orbit have been documented in the literature. Recognition of SFT of the orbit as a distinct pathologic entity and further follow-up of published cases are needed to determine the prognosis of this rare lesion.
眼眶孤立性纤维性肿瘤（SFT）是一种非常罕见的病变，可能会被误诊为纤维组织细胞瘤、血管外皮细胞瘤或其他眼眶肿瘤。我们报告一名62岁男性，他在因推测为神经纤维瘤而摘除左眼20年后，出现无痛性眼球突出。在T2加权磁共振成像（MRI）上，一个低信号肿瘤几乎占据了他整个左眼眶。没有颅内侵犯。眼眶内容剜除术获取的标本与SFT的组织学、免疫组织化学和电子显微镜检查结果一致。肿瘤波形蛋白和CD34染色呈阳性，但S-100蛋白和上皮膜抗原染色呈阴性。文献中仅记录了其他9例眼眶SFT病例。需要将眼眶SFT识别为一种独特的病理实体，并对已发表病例进行进一步随访，以确定这种罕见病变的预后。
