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[孕中期两次暴露后妊娠期水痘肺炎。血清预防的价值]

[Varicella pneumonia during pregnancy after double exposure in the 2nd trimester. Value of seroprophylaxis].

作者信息

Alonso A M, Perrotin F, Harchaoui Y, Body G, Lansac J

机构信息

Département de Gynécologie-Obstétrique, Reproduction Humaine et Médecine Foetale, CHU Bretonneau, Tours.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1999 Dec;28(8):838-41.

Abstract

We report on a case of varicella pneumonia at 29 weeks of gestation after double contact during the second trimester of pregnancy although passive immunotherapy by polyvalent immunoglobulins was used. Our case report highlights the difficulties of varicella pneumonia diagnosis that was here confirmed by seroconversion and the presence of pathognomonic microcalcifications, on a pulmonary X-ray, realized two years after pregnancy. Although the absence of publications asserting the efficacy of immunotherapy by polyvalent immunoglobulins to prevent maternal complications of varicella during pregnancy, they remain widely employed in such cases. Our point of view is that this indication must be revisited.

摘要

我们报告一例妊娠29周时发生的水痘肺炎病例,该孕妇在妊娠中期两次接触水痘病毒后发病,尽管使用了多价免疫球蛋白进行被动免疫治疗。我们的病例报告强调了水痘肺炎诊断的困难,本例通过血清转化以及产后两年进行的肺部X光检查发现特征性微钙化得以确诊。尽管目前尚无文献证实多价免疫球蛋白免疫治疗在预防孕期水痘产妇并发症方面的疗效,但在这类病例中仍广泛应用。我们认为必须重新审视这一适应证。

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