Manten G T, Derks J B, van Loon A M, Gerards L J, Bruinse H W
Divisie Perinatologie en Gynaecologie, Universitair Medisch Centrum Utrecht, locatie Wilhelmina Kinderziekenhuis, Postbus 85.090, 3508 AB Utrecht.
Ned Tijdschr Geneeskd. 2003 Oct 11;147(41):2029-32.
A 41-year-old woman with chickenpox in the third trimester of her pregnancy was admitted to the Intensive Care Unit of our hospital for ventilatory support. She was treated with aciclovir, amoxicillin-clavulanic acid and erythromycin. Her baby was delivered by forceps following placental abruption. After delivery, both mother and child recovered slowly but could eventually leave the hospital in good condition. If a pregnant woman without a prior history of varicella-zoster infection is exposed to a child that has chickenpox, passive immunisation with varicella-zoster immunoglobulin should be administered. This reduces the risk of maternal complications and may prevent a fetal varicella syndrome. If the mother has already developed chickenpox and there are serious complications, she should be treated with intravenous aciclovir. If possible, delivery should be delayed until 5 days after the onset of maternal chickenpox.
一名在妊娠晚期患水痘的41岁女性因呼吸支持被收治入我院重症监护病房。她接受了阿昔洛韦、阿莫西林 - 克拉维酸和红霉素治疗。她的婴儿在胎盘早剥后通过产钳助产分娩。产后，母婴恢复缓慢，但最终得以康复出院。如果既往无水痘 - 带状疱疹感染史的孕妇接触了患水痘的儿童，应给予水痘 - 带状疱疹免疫球蛋白进行被动免疫。这可降低母亲并发症的风险，并可能预防胎儿水痘综合征。如果母亲已经患上水痘且出现严重并发症，应给予静脉注射阿昔洛韦治疗。如有可能，分娩应推迟至母亲水痘发病后5天。
