Westerman D A, Speed B R, Prince H M
Peter MacCallum Cancer Institute, East Melbourne, Vic., Australia.
Pathology. 1999 Nov;31(4):393-4. doi: 10.1080/003130299104783.
We report a case of fatal disseminated fungal infection by Scedosporium prolificans which occurred in a patient with acute leukemia during induction chemotherapy. Rapid clinical deterioration despite high-dose empirical amphotericin B highlights both the pathogenicity of this fungus in immunocompromised hosts and its resistance to standard antifungal therapy.
我们报告了一例由多育赛多孢菌引起的致命播散性真菌感染病例，该病例发生在一名急性白血病患者的诱导化疗期间。尽管给予了高剂量经验性两性霉素B治疗，但患者临床病情仍迅速恶化，这凸显了这种真菌在免疫功能低下宿主中的致病性及其对标准抗真菌治疗的耐药性。
