Kniss D A
Department of Obstetrics and Gynecology, Ohio State University, College of Medicine and Public Health, Columbus 43210, USA.
J Soc Gynecol Investig. 1999 Nov-Dec;6(6):285-92. doi: 10.1016/s1071-5576(99)00034-9.
This review focuses on the role of cyclooxygenases in reproductive medicine and biology. The cyclooxygenase enzymes catalysis the role-limiting reactions for prostaglandins and thromboxane synthesis. Two separate isoforms, COX-1 and COX-2, are present, and differences in their roles are discussed in the context of inflammation and parturition.
本综述聚焦于环氧化酶在生殖医学与生物学中的作用。环氧化酶催化前列腺素和血栓素合成的限速反应。存在两种不同的同工型,即COX - 1和COX - 2,并在炎症和分娩的背景下讨论了它们作用的差异。