Sparks H V
Department of Physiology, Michigan State University, East Lansing, Michigan 48824, USA.
Am J Physiol. 1999 Dec;277(6 Pt 2):S164-73. doi: 10.1152/advances.1999.277.6.S164.
Students can learn a great deal about the peripheral circulation when teaching is based on five building blocks: hemodynamic principles, neurohumoral control, and three elements of local control of blood flow (metabolic, myogenic, and paracrine). Study of a particular special circulation starts with the application of these building blocks in the context of the function of that tissue. For example, control of skin blood flow is largely concerned with regulation of body temperature (neurohumoral control) and the response to injury (paracrine control). Regulation of coronary blood flow is almost entirely a matter of meeting the metabolic needs of the myocardium (metabolic control). By mixing and matching the five building blocks and keeping in mind the special functions of a particular tissue, students can master the peripheral circulation efficiently.
当教学基于五个基本要素展开时,学生能够深入了解外周循环:血流动力学原理、神经体液控制以及血流局部控制的三个要素(代谢、肌源性和旁分泌)。对特定特殊循环的研究始于在该组织功能的背景下应用这些基本要素。例如,皮肤血流的控制主要涉及体温调节(神经体液控制)和对损伤的反应(旁分泌控制)。冠状动脉血流的调节几乎完全是为了满足心肌的代谢需求(代谢控制)。通过将这五个基本要素进行组合搭配,并牢记特定组织的特殊功能,学生能够高效掌握外周循环。