Wang M C, Woung L C
Department of Ophthalmology, Taipei Municipal Yang-Ming Hospital, Taiwan, Republic of China.
J Cataract Refract Surg. 2000 Jan;26(1):56-61. doi: 10.1016/s0886-3350(99)00332-6.
To compare the formation and rates of posterior capsule opacification (PCO) in eyes with poly(methyl methacrylate) (PMMA) versus silicone intraocular lenses (IOLs) using an in vivo objective method.
Taipei Municipal Yang-Ming Hospital, Taipei, Taiwan, Republic of China.
This prospective study comprised 40 eyes with senile cataract receiving phacoemulsification with capsular implantation of an IOL from March to April 1997. The uneventful surgeries were performed using the stop and chop method by the same surgeon. Twenty eyes received a PMMA IOL (Pharmacia 812A) and 20, a silicone IOL (AMO SI-30NB). One year later, digital retroillumination images taken with the EAS-1000 anterior segment analysis system (Nidek) were used to analyze posterior capsule transparency over the central 3.0 and 5.0 mm optic zones and evaluate the degree of PCO over the central and peripheral zones.
Over the central 5.0 mm optic zone, mean transparency of the capsule was 87.71% +/- 11.35% (SD) in the silicone group and 79.22% +/- 21.10% in the PMMA group (P = .17). Over the central 3.0 mm optic zone, the means were 97.17% +/- 5.96% and 86.32% +/- 19.60%, respectively (P = .048). Mean opacity in the central zone was 75.18 +/- 13.22 digital opacity units (OUs) in the silicone group and 80.24 +/- 7.93 OUs in the PMMA group (P = .18). The means in the peripheral zone were 88.49 +/- 18.47 OUs and 90.35 +/- 9.98 OUs, respectively (P = .71).
The posterior capsule in the silicone IOL group was more transparent than in the PMMA IOL group over the central 3.0 mm optic zone after 1 year follow-up.
采用体内客观方法比较聚甲基丙烯酸甲酯（PMMA）人工晶状体与硅酮人工晶状体（IOL）植入眼后囊膜混浊（PCO）的形成及发生率。
中国台湾地区台北市阳明医院。
本前瞻性研究纳入了1997年3月至4月接受白内障超声乳化吸除术并囊袋内植入IOL的40例老年性白内障患者的40只眼。由同一位外科医生采用拦截劈核技术进行顺利的手术。20只眼植入PMMA人工晶状体（Pharmacia 812A），20只眼植入硅酮人工晶状体（AMO SI-30NB）。1年后，使用EAS-1000眼前节分析系统（尼德克）拍摄的数字后照图像分析中央3.0和5.0 mm光学区的后囊膜透明度，并评估中央和周边区域的PCO程度。
随访1年后，在中央5.0 mm光学区，硅酮组囊膜平均透明度为87.71%±11.35%（标准差），PMMA组为79.22%±21.10%（P = 0.17）。在中央3.0 mm光学区，平均值分别为97.17%±5.96%和86.32%±19.60%（P = 0.048）。中央区平均混浊度在硅酮组为75.18±13.22数字混浊单位（OU），PMMA组为80.24±7.93 OU（P = 0.18）。周边区平均值分别为88.49±18.47 OU和90.35±9.98 OU（P = 0.71）。
随访1年后，在中央3.0 mm光学区内，硅酮人工晶状体组的后囊膜比PMMA人工晶状体组更透明。
