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成熟度和年龄对大鼠皮肤拉伸强度、松弛及力学恢复的影响

Tensile strength, relaxation and mechanical recovery in rat skin as influenced by maturation and age.

作者信息

Vogel H G

出版信息

J Med. 1976;7(2):177-88.

PMID:1064684
Abstract

Several mechanical parameters were measured in skin strips of rats at various ages (1, 2, 4, 12 or 24 months). Ultimate load and tensile strength increased during the maturation process and reached a maximum at 12 months. In old animals (24 months) a decrease of these parameters was noted. After various preloads relaxation was measured. Relaxation could be described mathematically as a function of logarithm of time. The relaxation coefficient decreased during the maturation as well as during the ageing period. After unloading up to 1/5 initial load mechanical recovery was measured. Mechanical recovery was increased depending on age during the whole life span. It is concluded that various components of viscoelatic behaviour are influenced differently by the maturation and the ageing process.

摘要

在不同年龄(1、2、4、12或24个月)的大鼠皮肤条上测量了几个力学参数。极限负荷和抗张强度在成熟过程中增加,并在12个月时达到最大值。在老年动物(24个月)中,这些参数出现下降。在施加各种预负荷后测量松弛情况。松弛情况可以用时间对数的函数进行数学描述。松弛系数在成熟过程以及衰老期间均下降。在卸载至初始负荷的1/5后测量力学恢复情况。在整个寿命期内,力学恢复随年龄增加。得出的结论是,粘弹性行为的各个组成部分受成熟和衰老过程的影响不同。

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