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年龄增长对宫腔镜子宫内膜切除术治疗功能失调性子宫出血疗效的影响。

The effect of increasing age on the outcome of hysteroscopic endometrial resection for management of dysfunctional uterine bleeding.

作者信息

Seidman D S, Bitman G, Mashiach S, Hart S, Goldenberg M

机构信息

Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel-Hashomer, Israel.

出版信息

J Am Assoc Gynecol Laparosc. 2000 Feb;7(1):115-9. doi: 10.1016/s1074-3804(00)80020-1.

Abstract

STUDY OBJECTIVE

To determine the outcome of hysteroscopic endometrial resection for dysfunctional uterine bleeding according to women's age.

DESIGN

Long-term follow-up by telephone interview (Canadian Task Force classification II-2).

SETTING

University-affiliated medical center. Patients. One hundred sixty-nine women with abnormal uterine bleeding unresponsive to conservative medical management.

INTERVENTION

Hysteroscopic endometrial resection.

MEASUREMENTS AND MAIN RESULTS

Questionnaires were completed for 162 (95.9%) patients with mean +/- SD follow-up of 32 +/- 17 months. The frequency of postoperative complications was not related to age. After ablation, the rate of amenorrhea was significantly higher in 31 women age 50 years or older than in younger women (p <0.001), and also in 72 women age 45 to 49 than in 59 age 44 or less (p <0.05). Complete relief of dysmenorrhea was achieved significantly more often in women age 45 to 49 (p <0.005) and 50 or older (p <0.05) than in those age 44 or younger. Dissatisfaction with the outcome of endometrial resection was uncommon, but most frequent among women age 44 or younger (p <0.10). There was no difference in the proportion of women requiring second ablation or hysterectomy in any age group.

CONCLUSION

Significantly higher rates of amenorrhea and complete relief of dysmenorrhea after endometrial resection are achieved in older than in younger women.

摘要

研究目的

根据女性年龄确定宫腔镜下子宫内膜切除术治疗功能失调性子宫出血的疗效。

设计

通过电话访谈进行长期随访(加拿大工作组分类II-2)。

地点

大学附属医院。患者:169例对保守药物治疗无效的异常子宫出血女性。

干预措施

宫腔镜下子宫内膜切除术。

测量指标及主要结果

对162例(95.9%)患者进行了问卷调查,平均随访时间为32±17个月。术后并发症的发生率与年龄无关。切除术后,50岁及以上的31例女性闭经率显著高于年轻女性(p<0.001),45至49岁的72例女性闭经率也高于44岁及以下的59例女性(p<0.05)。45至49岁(p<0.005)和50岁及以上(p<0.05)的女性痛经完全缓解的比例显著高于44岁及以下的女性。对子宫内膜切除术结果不满意的情况并不常见,但在44岁及以下的女性中最为常见(p<0.10)。各年龄组中需要二次切除或子宫切除的女性比例没有差异。

结论

子宫内膜切除术后,老年女性的闭经率和痛经完全缓解率显著高于年轻女性。

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