Rourke S B, Halman M H, Bassel C
Department of Psychiatry, University of Toronto, ONT, Canada.
J Clin Exp Neuropsychol. 1999 Dec;21(6):757-68. doi: 10.1076/jcen.21.6.757.852.
Ninety-one adults with HIV-infection who varied in the concordance between their subjective memory complaints (or metamemory) on the Patient's Assessment of Own Functioning (Chelune, Heaton, & Lehman, 1986) and their memory performance on the California Verbal Learning Test (CVLT), were compared on the Beck Depression Inventory (BDI), and on neuropsychological (NP) tests of attention, language, psychomotor speed, and conceptual problem-solving. Subjects with low memory complaints and normal CVLT performance (n = 29) had low BDI scores and were normal in all other NP abilities. Subjects with high memory complaints and impaired CVLT performance (n = 20) had elevations on the BDI as well as NP impairments in psychomotor speed and category fluency. Subjects with low memory complaints but impaired CVLT performance (n = 16) had low BDI scores and were selectively impaired in conceptual problem-solving. Subjects with high memory complaints but normal CVLT performance (n = 26) had high BDI scores and normal NP functioning in all other abilities. These results suggest that there are at least two key determinants to metamemory inaccuracy in HIV-infection, namely, frontal executive impairments and mood disturbance.
对91名感染HIV的成年人进行了比较，这些成年人在患者自我功能评估（Chelune、Heaton和Lehman，1986年）中的主观记忆抱怨（或元记忆）与他们在加利福尼亚言语学习测试（CVLT）中的记忆表现之间的一致性各不相同。比较内容包括贝克抑郁量表（BDI）以及注意力、语言、心理运动速度和概念性问题解决方面的神经心理学（NP）测试。记忆抱怨少且CVLT表现正常的受试者（n = 29）BDI得分低，其他所有NP能力均正常。记忆抱怨多且CVLT表现受损的受试者（n = 20）BDI得分升高，心理运动速度和类别流畅性方面存在NP损伤。记忆抱怨少但CVLT表现受损的受试者（n = 16）BDI得分低，在概念性问题解决方面存在选择性损伤。记忆抱怨多但CVLT表现正常的受试者（n = 26）BDI得分高，其他所有能力的NP功能均正常。这些结果表明，HIV感染中元记忆不准确至少有两个关键决定因素，即额叶执行功能损伤和情绪障碍。
