Mehra P, Clancy C, Wu J
Boston University School of Dental Medicine, USA.
J Am Dent Assoc. 2000 Jan;131(1):67-71. doi: 10.14219/jada.archive.2000.0021.
Sodium hypochlorite, or NaOCl, is one of the most commonly used irrigating solutions in endodontic practice. Its clinically proven antibacterial, solvent and lubricating properties make it a very appealing choice as an intracanal medicament.
The authors present a case of facial hematoma formation after an inadvertent injection of NaOCl into the periapical tissues. The NaOCl solution caused extensive tissue destruction. Management of the condition required the hospitalization, intravenous antibiotic therapy and multiple intraoral surgical incisions to facilitate drainage.
Use of NaOCl must be confined to the root canal system. This report reviews this intracanal medicament's potential toxicity and emphasizes the need for clinicians to remain cognizant of possible problems while using the solution.
次氯酸钠（NaOCl）是牙髓病治疗中最常用的冲洗液之一。其经临床验证的抗菌、溶解和润滑特性使其成为一种非常有吸引力的根管内药物选择。
作者报告了一例因意外将NaOCl注射到根尖周组织后形成面部血肿的病例。NaOCl溶液导致了广泛的组织破坏。该病症的治疗需要住院、静脉注射抗生素治疗以及多次口腔内手术切口以促进引流。
NaOCl的使用必须局限于根管系统。本报告回顾了这种根管内药物的潜在毒性，并强调临床医生在使用该溶液时需要意识到可能出现的问题。
