绿僵菌产生的接合孢子素D和两种新的细胞松弛素。

Zygosporin D and two new cytochalasins produced by the fungus Metarrhizium anisopliae.

作者信息

Fujii Y, Tani H, Ichinoe M, Nakajima H

机构信息

Department of Agricultural Chemistry, Faculty of Agriculture, Tottori University, Koyama, Tottori 680-8553, Japan.

出版信息

J Nat Prod. 2000 Jan;63(1):132-5. doi: 10.1021/np990331t.

DOI:10.1021/np990331t

PMID:10650095

Abstract

Zygosporin D (3) and two new cytochalasins (4 and 5) were isolated from the culture filtrate of the fungus Metarrhizium anisopliae and characterized on the basis of their spectral data and chemical conversions. The new cytochalasins, 4 and 5, were determined to be deacetylcytochalasin C and (6R,16S,18R,21R)-18,21-dihydroxy-16, 18-dimethyl-10-phenyl[11]cytochalasa-13(E),19(E)-diene-1,7,17-trio ne, respectively. Of these three cytochalasins, only zygosporin D is an effective inhibitor of shoot elongation of rice seedlings.

摘要

从绿僵菌的培养滤液中分离出了接合孢子素D（3）和两种新的细胞松弛素（4和5），并根据它们的光谱数据和化学转化对其进行了表征。新的细胞松弛素4和5分别被确定为脱乙酰细胞松弛素C和（6R，16S，18R，21R）-18，21-二羟基-16，18-二甲基-10-苯基[11]细胞松弛素-13（E），19（E）-二烯-1，7，17-三酮。在这三种细胞松弛素中，只有接合孢子素D是水稻幼苗茎伸长的有效抑制剂。