Elford J, Wells I, Cowie J, Hurlock C, Sanders H
Department of Radiology, Derriford Hospital, Plymouth, UK.
Clin Radiol. 2000 Jan;55(1):36-9. doi: 10.1053/crad.1999.0332.
To test the ability of computerized strain-gauge plethysmography to act as a screening test for lower limb deep venous thrombosis (DVT).
Over an 8-month period, all patients referred to our Medical Assessment Unit with suspected lower limb DVT were considered for inclusion in the study. Each patient underwent both plethysmography and ascending venography within 24 h, and the presence or absence of thrombus in the popliteal, superficial femoral or iliac veins was noted. The results of the two tests were then used to determine the accuracy of computerized strain-gauge plethysmography in detecting above knee DVT.
The screening tests and venograms of 239 patients referred with clinically suspected lower limb DVT were compared. The false negative rate of plethysmography was 15.4%, which is significantly different from the 4.8% claimed by the manufacturers of this device (P = 0.00003).
In a population of acute admissions with suspected lower limb DVT, computerized strain-gauge plethysmography is not suitable for use as a screening test due to an unacceptably high proportion of false negative screens.
测试计算机应变计体积描记法作为下肢深静脉血栓形成（DVT）筛查试验的能力。
在8个月的时间里，所有因疑似下肢DVT转诊至我们医学评估单元的患者均被纳入研究。每位患者在24小时内均接受了体积描记法和上行静脉造影，并记录腘静脉、股浅静脉或髂静脉中有无血栓。然后用这两项检查的结果来确定计算机应变计体积描记法检测膝上DVT的准确性。
比较了239例临床疑似下肢DVT患者的筛查试验和静脉造影结果。体积描记法的假阴性率为15.4%，与该设备制造商声称的4.8%有显著差异（P = 0.00003）。
在疑似下肢DVT的急性入院患者群体中，由于计算机应变计体积描记法的假阴性筛查比例高得令人无法接受，因此不适合用作筛查试验。
