Engwerda C R, Kaye P M
Dept of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK WC1E 7HT.
Immunol Today. 2000 Feb;21(2):73-8. doi: 10.1016/s0167-5699(99)01549-2.
The immune response to infection can vary markedly in different organs of the same animal. In some organs, the infection can resolve with subsequent immunity to re-infection, whereas in other organs, pathogens can persist. Here, Christian Engwerda and Paul Kaye highlight the importance of defining organ-specific immune mechanisms for developing strategies that deal effectively with infectious diseases and their associated pathologies.
