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脊髓麻醉在先兆子痫患者中安全吗?

Is spinal anaesthesia safe in pre-eclamptic toxaemia patients?

作者信息

Ahmed S M, Khan R M, Bano S, Ajmani P, Kumar A

机构信息

Department of Anaesthesiology, JN Medical College, AMU, Aligarh.

出版信息

J Indian Med Assoc. 1999 May;97(5):165-8.

PMID:10652883
Abstract

Thirty-three patients of pre-eclamptic toxaemia underwent caesarean section (CS) under general anaesthesia (n = 16) and spinal anaesthesia (n = 17). The Apgar score at 1, 5 and 10 minutes of the babies following spinal anaesthesia (SA) were only marginally better than that of general anaesthesia (GA; P > 0.05). The incidence of complication following GA (68.8%) were significantly (P < 0.05) more than that of SA (47.1%). Commonest complications following GA were intra-operative hypertension (68.8%) followed by difficult intubation (25%), pulmonary oedema (12.8%), delayed recovery (12.8%) and mortality (4.3%). While following SA complications were intra-operative hypotension (47.1%), difficult SA (29.4%) and intra-operative vomiting (5.9%). The nature of complications following GA were more serious which may even lead to mortality (4.3%), whereas following SA it was less serious and easily manageable. Hence SA is not as unsafe as it is thought.

摘要

33例先兆子痫患者在全身麻醉(n = 16)和脊髓麻醉(n = 17)下行剖宫产术(CS)。脊髓麻醉(SA)后婴儿1分钟、5分钟和10分钟的阿氏评分仅略高于全身麻醉(GA)(P>0.05)。全身麻醉(GA)后并发症的发生率(68.8%)显著高于脊髓麻醉(SA)(47.1%)(P<0.05)。全身麻醉后最常见的并发症是术中高血压(68.8%),其次是插管困难(25%)、肺水肿(12.8%)、苏醒延迟(12.8%)和死亡率(4.3%)。而脊髓麻醉后的并发症是术中低血压(47.1%)、脊髓麻醉困难(29.4%)和术中呕吐(5.9%)。全身麻醉后并发症的性质更严重,甚至可能导致死亡(4.3%),而脊髓麻醉后并发症则较轻且易于处理。因此,脊髓麻醉并不像人们认为的那样不安全。

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Is spinal anaesthesia safe in pre-eclamptic toxaemia patients?脊髓麻醉在先兆子痫患者中安全吗?
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Subarachnoid block for caesarean section in severe preeclampsia.重度子痫前期剖宫产蛛网膜下腔阻滞
J Anaesthesiol Clin Pharmacol. 2011 Apr;27(2):169-73. doi: 10.4103/0970-9185.81821.