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重度子痫前期剖宫产蛛网膜下腔阻滞

Subarachnoid block for caesarean section in severe preeclampsia.

作者信息

Chaudhary Sujata, Salhotra Rashmi

机构信息

Department of Anaesthesiology and Critical Care, UCMS and GTB Hospital, Dilshad Garden, Delhi - 110 095, India.

出版信息

J Anaesthesiol Clin Pharmacol. 2011 Apr;27(2):169-73. doi: 10.4103/0970-9185.81821.

DOI:10.4103/0970-9185.81821
PMID:21772674
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3127293/
Abstract

Pregnancy-induced hypertension constitutes a major cause of morbidity and mortality in developing nations and it complicates about 6-8% of pregnancies. Severe preeclampsia poses a dilemma for the anesthesiologist especially in emergency situations where caesarean deliveries are planned for uninvestigated or partially investigated parturients. This article is aimed to review the literature with regards to the type of anesthesia for such situations. A thorough search of literature was conducted on PubMed, EMBASE, and Google to retrieve the articles. Studies on parturients with severe preeclampsia, undergoing caesarean section, were included in this article. There is growing evidence to support the use of subarachnoid block in such situations when the platelet counts are >80,000 mm(-3). Better hemodynamic stability with the use of low-dose local anesthetic along with additives and better neonatal outcomes has been found with the use of subarachnoid block when compared to general anesthesia.

摘要

妊娠高血压是发展中国家发病和死亡的主要原因之一,约6-8%的妊娠会出现并发症。重度子痫前期给麻醉医生带来了难题,尤其是在计划为未做检查或部分检查的产妇进行剖宫产的紧急情况下。本文旨在回顾此类情况下麻醉类型的相关文献。通过在PubMed、EMBASE和谷歌上全面检索文献来获取文章。本文纳入了对重度子痫前期产妇进行剖宫产的研究。越来越多的证据支持,当血小板计数>80,000/mm³时,在这种情况下使用蛛网膜下腔阻滞。与全身麻醉相比,使用低剂量局部麻醉药加添加剂的蛛网膜下腔阻滞具有更好的血流动力学稳定性和更好的新生儿结局。

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Subarachnoid block for caesarean section in severe preeclampsia.重度子痫前期剖宫产蛛网膜下腔阻滞
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2
Spinal block caesarean section in parturients with pregnancy-induced hypertension.妊娠高血压产妇的脊髓阻滞剖宫产术
East Afr Med J. 1998 Apr;75(4):227-31.
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Int J Obstet Anesth. 2005 Apr;14(2):108-13. doi: 10.1016/j.ijoa.2004.10.011.
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[Spinal or epidural anaesthesia for caesarean section? Compared opinions].[剖宫产的脊髓麻醉还是硬膜外麻醉?对比观点]
Minerva Anestesiol. 2001 Sep;67(9 Suppl 1):169-74.
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Failure of subarachnoid block in caesarean section.
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Height-based dosing algorithm of bupivacaine in spinal anaesthesia for decreasing maternal hypotension in caesarean section without prophylactic fluid preloading and vasopressors: study protocol for a randomised controlled non-inferiority trial.基于身高的布比卡因椎管内麻醉剂量算法在剖宫产中减少产妇低血压:一项无预防性液体预充和血管加压素的随机对照非劣效性试验研究方案。
BMJ Open. 2019 May 16;9(5):e024912. doi: 10.1136/bmjopen-2018-024912.
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Correlation between bleeding times and platelet counts in women with preeclampsia undergoing cesarean section.子痫前期剖宫产女性出血时间与血小板计数的相关性。
Anesthesiology. 1989 Aug;71(2):188-91. doi: 10.1097/00000542-198908000-00003.

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Patient Saf Surg. 2020 Mar 31;14:9. doi: 10.1186/s13037-020-00234-w. eCollection 2020.
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Comparing the Hemodynamic Effects of Spinal Anesthesia in Preeclamptic and Healthy Parturients During Cesarean Section.剖宫产术中比较脊髓麻醉对先兆子痫产妇和健康产妇的血流动力学影响
Anesth Pain Med. 2016 Jun 5;6(3):e11519. doi: 10.5812/aapm.11519. eCollection 2016 Jun.
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Anaesthetic management for emergency caesarean section in a patient with an untreated recently diagnosed phaeochromocytoma.一名近期诊断为嗜铬细胞瘤但未接受治疗的患者行急诊剖宫产的麻醉管理。
Indian J Anaesth. 2011 Nov;55(6):614-7. doi: 10.4103/0019-5049.90622.

本文引用的文献

1
Spinal subarachnoid hematoma following spinal anesthesia in a patient with HELLP syndrome.HELLP 综合征患者行脊髓麻醉后发生脊髓蛛网膜下腔血肿。
Int J Obstet Anesth. 2010 Jan;19(1):87-91. doi: 10.1016/j.ijoa.2009.05.007. Epub 2009 Nov 27.
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General versus neuraxial anaesthesia for caesarean section: impact on the duration of hospital stay.剖宫产的全身麻醉与椎管内麻醉:对住院时间的影响。
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Hemodynamic changes associated with spinal anesthesia for cesarean delivery in severe preeclampsia.重度子痫前期剖宫产脊髓麻醉相关的血流动力学变化
Anesthesiology. 2008 May;108(5):802-11. doi: 10.1097/01.anes.0000311153.84687.c7.
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The role of the anaesthetist in the management of the pre-eclamptic patient.麻醉医生在子痫前期患者管理中的作用。
Curr Opin Anaesthesiol. 2007 Jun;20(3):168-74. doi: 10.1097/ACO.0b013e328136c1ac.
5
Obstetric anesthesia controversies: vasopressor choice for postspinal hypotension during cesarean delivery.产科麻醉争议:剖宫产术中脊髓麻醉后低血压的血管升压药选择
Int Anesthesiol Clin. 2007 Winter;45(1):115-32. doi: 10.1097/AIA.0b013e31802b8d53.
6
The anticoagulated parturient.接受抗凝治疗的产妇。
Int Anesthesiol Clin. 2007 Winter;45(1):71-81. doi: 10.1097/AIA.0b013e31802b8ad4.
7
Ultra-low dose combined spinal-epidural anaesthesia for Caesarean section in severe pre-eclampsia.超低剂量腰麻-硬膜外联合麻醉用于重度子痫前期患者剖宫产术
Anaesthesia. 2006 May;61(5):511-2. doi: 10.1111/j.1365-2044.2006.04630.x.
8
Spinal anesthesia-induced hypotension: a risk comparison between patients with severe preeclampsia and healthy women undergoing preterm cesarean delivery.脊髓麻醉引起的低血压:重度子痫前期患者与接受早产剖宫产的健康女性之间的风险比较。
Anesth Analg. 2005 Sep;101(3):869-875. doi: 10.1213/01.ANE.0000175229.98493.2B.
9
Spinal versus epidural anesthesia for cesarean delivery in severe preeclampsia: a prospective randomized, multicenter study.重度子痫前期剖宫产术的脊髓麻醉与硬膜外麻醉:一项前瞻性随机多中心研究
Anesth Analg. 2005 Sep;101(3):862-868. doi: 10.1213/01.ANE.0000160535.95678.34.
10
A randomized trial comparing low-dose combined spinal-epidural anesthesia and conventional epidural anesthesia for cesarean section in severe preeclampsia.一项比较低剂量腰麻-硬膜外联合麻醉与传统硬膜外麻醉用于重度子痫前期剖宫产的随机试验。
Acta Anaesthesiol Belg. 2005;56(2):155-62.