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动脉内注射普鲁卡因青霉素后发生坏疽。

Gangrene following intra-arterial injection of procaine penicillin.

作者信息

Sengupta S

出版信息

Aust N Z J Med. 1976 Feb;6(1):71-3. doi: 10.1111/j.1445-5994.1976.tb03295.x.

DOI:10.1111/j.1445-5994.1976.tb03295.x
PMID:1065306
Abstract

Irreversible ischaemic gangrene of the upper limb developed in a one-year-old child after an unintentional intra-arterial injection of procaine penicillin. The hand needed amputation. Arterial embolization phenomenon along with intense vasospasm appears to have been responsible for this rare complication. Unintentional intra-arterial injection of penicillin intended for intra-muscular use may lead to disastrous consequences. Regional tissue necrosis has been described previously but ischaemia leading to gangrene of an extremity has not been reported. The following is a case report of a child who developed such a gangrene in his hand which had to be amputated.

摘要

一名一岁儿童在无意中进行动脉内注射普鲁卡因青霉素后,出现了上肢不可逆性缺血性坏疽。手部需要截肢。动脉栓塞现象以及强烈的血管痉挛似乎是导致这一罕见并发症的原因。无意中将用于肌肉注射的青霉素进行动脉内注射可能会导致灾难性后果。此前曾有局部组织坏死的描述,但导致肢体坏疽的缺血情况尚未见报道。以下是一名儿童手部发生此类坏疽并不得不截肢的病例报告。

相似文献

1
Gangrene following intra-arterial injection of procaine penicillin.动脉内注射普鲁卡因青霉素后发生坏疽。
Aust N Z J Med. 1976 Feb;6(1):71-3. doi: 10.1111/j.1445-5994.1976.tb03295.x.
2
[The Nicolau syndrome in children (author's transl)].儿童尼科拉乌综合征(作者译)
Z Kinderchir. 1981 Apr;32(4):367-70. doi: 10.1055/s-2008-1063286.
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[Gangrene of the hand due to accidental intra-arterial injection of floxacilline: about a case].[因意外动脉内注射氟氯西林导致手部坏疽:病例报告]
Pan Afr Med J. 2016 Dec 6;25:221. doi: 10.11604/pamj.2016.25.221.10803. eCollection 2016.
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Tissue damage caused by the intramuscular injection of long-acting penicillin.长效青霉素肌肉注射引起的组织损伤。
Pediatrics. 1985 Apr;75(4):741-4.
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Inadvertent intra-arterial injection of penicillin: an unseen danger.意外动脉内注射青霉素:一种潜在的危险。
Pediatrics. 1985 Apr;75(4):785-6.
6
Gangrene of the hand and forearm after inadvertent intra-arterial injection of pyrazole. A case report.
S Afr Med J. 1985 Sep 28;68(7):491-2.
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[Apropos of 2 cases of arterial embolism following an injection of oily compounds].[关于2例注射油性化合物后发生动脉栓塞的病例]
Lyon Med. 1971 Feb 28;225(4):305-8.
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Gangrene after penicillin injection (a case report).青霉素注射后坏疽(一例报告)。
Turk J Pediatr. 1995 Jan-Mar;37(1):67-71.
9
[Transverse syndrome following intramuscular injection of penicillin].
Z Arztl Fortbild (Jena). 1989;83(10):537-8.
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Gangrene of the upper extremity following intra-arterial injection of drugs. A case report and review of the literature.动脉内注射药物后上肢坏疽。病例报告及文献复习。
Clin Orthop Relat Res. 1984 Sep(188):223-9.

引用本文的文献

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J Pediatr Intensive Care. 2018 Mar;7(1):43-45. doi: 10.1055/s-0037-1601336. Epub 2017 Mar 20.
2
A misplaced intramuscular injection and limb-threatening ischemia.一次误行的肌肉注射与危及肢体的缺血。
J Family Med Prim Care. 2017 Jul-Sep;6(3):680-682. doi: 10.4103/2249-4863.222058.
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Gastrointestinal instrumentation, bacteraemia, and endocarditis.胃肠道器械操作、菌血症与心内膜炎。
Gut. 1983 Nov;24(11):1078-93. doi: 10.1136/gut.24.11.1078.