Berry R G, Morrison J A, Watts J W, Anagnost J W, Gonzalez J J
Columbus County Hospital, Whiteville, NC, USA.
South Med J. 2000 Jan;93(1):74-5.
Physicians must have a high index of suspicion when patients have unexplained prolongation of the prothrombin time and bleeding in the absence of detectable warfarin. Several common rodenticides contain modified versions of warfarin that are not detectable in standard warfarin assays. We present a case of surreptitious brodifacoum ingestion in a patient who had years of unexplained bleeding and negative warfarin levels.
当患者在没有可检测到的华法林的情况下出现凝血酶原时间不明原因延长和出血时,医生必须保持高度怀疑。几种常见的灭鼠剂含有华法林的改良版本,在标准华法林检测中无法检测到。我们报告一例患者隐匿摄入溴敌隆的病例,该患者多年来有不明原因的出血且华法林水平呈阴性。