Wolf R, Wolf R F, Hoekstra H J
Department of Diagnostic Radiology, Groningen University Hospital, The Netherlands.
Skeletal Radiol. 1999 Dec;28(12):710-3. doi: 10.1007/s002560050578.
Osteosarcoma (osteogenic sarcoma) metastasizes primarily to the lung. With the introduction of neoadjuvant chemotherapy as part of the treatment, the overall and disease-free survival rates have dramatically improved. In this case report, a young man with multiple soft tissue and bone metastases, including a rare large bone-forming retroperitoneal metastasis, is described. Despite the extensive extrapulmonary metastases, the patient did not develop pulmonary metastases in the 4 years following initial presentation of the primary tumour.
骨肉瘤（成骨肉瘤）主要转移至肺部。随着新辅助化疗作为治疗的一部分引入，总体生存率和无病生存率显著提高。在本病例报告中，描述了一名患有多处软组织和骨转移的年轻男性，其中包括罕见的巨大骨形成性腹膜后转移。尽管有广泛的肺外转移，但该患者在原发性肿瘤首次出现后的4年中未发生肺转移。
