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[与风湿性多肌痛相关的主动脉夹层动脉瘤:一例报告]

[The dissecting aortic aneurysm associated with polymyalgia rheumatica: a case report].

作者信息

Iroi A, Miwa H, Iijima M, Fukae J, Hatori K, Tanaka S, Yano T, Mizuno Y

机构信息

Department of Neurology, Juntendo University Urayasu Hospital, Chiba, Japan.

出版信息

No To Shinkei. 1999 Dec;51(12):1051-4.

Abstract

We report a patient with a dissecting aortic aneurysm associated with polymyalgia rheumatica (PMR). The patient is a 55-year-old Japanese man without a history of hypertension, diabetes mellitus and syphilis. He was admitted to an emergency hospital because of severe back pain, and was diagnosed as having a dissecting aneurysm of the descending aorta. After the admission, he began to notice severe muscle pain in his bilateral shoulder. Although his back pain gradually improved, his muscle pain progressively worsened, and his lower extremities were also involved. Then, he was introduced to our hospital. On neurological examination, he was alert and oriented. His cranial nerves were all intact. There was no muscle weakness nor sensory disturbance. Laboratory studies revealed that his erhythrocyte sedimentation rate was extremely high without elevation of the serum level of creatine phoshpokinase, rheumatoid factors and c-reactive protein. He was diagnosed as having PMR, and oral administration of prednisolone++ was started. Within several days, his muscle pain dramatically disappeared. As is known, there is a close relationship between PMR and temporal arteritis of giant cell arteritis. In general, PMR is a benign disease and responds well to steroid therapy, and prevalence of the giant cell arteritis is low in Japanese people. However, it should be kept in mind that the dissecting aneurysm is a relevant, severe complication of PMR because arteritis can be latently present in PMR.

摘要

我们报告一例患有与风湿性多肌痛(PMR)相关的主动脉夹层动脉瘤的患者。该患者是一名55岁的日本男性,无高血压、糖尿病和梅毒病史。他因严重背痛入住急诊医院,被诊断为降主动脉夹层动脉瘤。入院后,他开始注意到双侧肩部严重肌肉疼痛。尽管他的背痛逐渐好转,但肌肉疼痛却逐渐加重,且累及下肢。随后,他被转诊至我院。神经系统检查显示,他神志清醒、定向力正常。其颅神经均完整。无肌肉无力及感觉障碍。实验室检查发现,他的红细胞沉降率极高,而血清肌酸磷酸激酶、类风湿因子和C反应蛋白水平未升高。他被诊断为患有PMR,并开始口服泼尼松龙。数天内,他的肌肉疼痛显著消失。众所周知,PMR与巨细胞动脉炎的颞动脉炎密切相关。一般而言,PMR是一种良性疾病,对类固醇治疗反应良好,且巨细胞动脉炎在日本人中的患病率较低。然而,应牢记主动脉夹层动脉瘤是PMR的一种相关严重并发症,因为动脉炎可能在PMR中潜伏存在。

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