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菲律宾城市贫困住区的结核病

Tuberculosis in the urban poor settlements in the Philippines.

作者信息

Tupasi T E, Radhakrishna S, Quelapio M I, Villa M L, Pascual M L, Rivera A B, Sarmiento A, Co V M, Sarol J N, Beltran G, Legaspi J D, Mangubat N V, Reyes A C, Solon M, Solon F S, Burton L, Mantala M J

机构信息

Tropical Disease Foundation, Makati Medical Center, Makati City, The Philippines.

出版信息

Int J Tuberc Lung Dis. 2000 Jan;4(1):4-11.

PMID:10654637
Abstract

SETTING

Urban poor settlements in the Philippines.

OBJECTIVE

To determine the magnitude of the tuberculosis problem in urban poor settlements in comparison with urban areas studied in the Nationwide Tuberculosis Prevalence Survey.

STUDY DESIGN AND METHOD

A multistage cluster survey of BCG scar, tuberculin test, chest radiography and sputum examination for bacillary disease, in urban poor areas.

RESULTS

The prevalences of culture-positive and smear-positive tuberculosis were 17.5 +/- 2.3 (95% CI 13.3-22.4) and 7.9 +/- 2.3 per thousand (95% CI 2.611.5), respectively. Extrapolated to the total population, the rates in the urban poor settlements were 12.4 +/- 1.7 (95% CI 9.6-16.2) and 5.6 +/- 1.6 per thousand population (95% CI 1.3-8.3), respectively. The prevalence of active pulmonary tuberculosis in subjects aged 10 years or more was 66 +/- 5.6/1000 (95% CI 55-77). The BCG vaccination rate was 72%. The overall prevalence of tuberculosis infection was 66%, and 39% in those aged 5-9 years, corresponding to an annual risk of infection (ARI) of 6.5%.

CONCLUSION

The problem of tuberculosis was substantial in the urban poor settlements, and was appreciably worse than that in the general urban population.

摘要

研究背景

菲律宾城市贫困社区。

研究目的

与全国结核病患病率调查中所研究的城市地区相比,确定城市贫困社区结核病问题的严重程度。

研究设计与方法

在城市贫困地区对卡介苗疤痕、结核菌素试验、胸部X光检查以及痰涂片检查进行多阶段整群抽样调查。

研究结果

培养阳性肺结核和涂片阳性肺结核的患病率分别为每千人17.5±2.3(95%置信区间13.3 - 22.4)和7.9±2.3(95%置信区间2.6 - 11.5)。推算至城市贫困社区总人口,患病率分别为每千人12.4±1.7(95%置信区间9.6 - 16.2)和5.6±1.6(95%置信区间1.3 - 8.3)。10岁及以上人群中活动性肺结核患病率为66±5.6/1000(95%置信区间55 - 77)。卡介苗接种率为72%。结核病感染总体患病率为66%,5 - 9岁儿童为39%,对应的年感染风险(ARI)为6.5%。

研究结论

城市贫困社区结核病问题严重,且明显比城市普通人群更为严峻。

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