• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

流行病学在辐射有害效应检测中的作用。

The role of epidemiology in the detection of harmful effects of radiation.

作者信息

Stewart A

机构信息

Department of Public Health and Epidemiology, University of Birmingham, Edgbaston, Birmingham, United Kingdom.

出版信息

Environ Health Perspect. 2000 Feb;108(2):93-6. doi: 10.1289/ehp.0010893.

DOI:10.1289/ehp.0010893
PMID:10656847
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1637879/
Abstract

Data relating to acute injuries of atomic bomb survivors show that the life span study cohort is biased in favor of exceptionally low levels of radiosensitivity. These data also show that factors influencing the death rates of this cohort include irreversible damage to the immune system. These impressions are still awaiting confirmation. Meanwhile, the Oxford Survey of Childhood Cancers and surveys of nuclear workers show that at low dose levels the cancer risk is much greater than estimates based on atomic bomb survivors; the special association between leukemia and radiation is an exclusively high dose effect, and levels of radiosensitivity are much lower in the middle of the life span than at either extreme.

摘要

有关原子弹幸存者急性损伤的数据表明，寿命研究队列偏向于对辐射敏感性极低的人群。这些数据还表明，影响该队列死亡率的因素包括免疫系统的不可逆损伤。这些观点仍有待证实。与此同时，牛津儿童癌症调查和核工业工人调查显示，在低剂量水平下，癌症风险远高于基于原子弹幸存者的估计；白血病与辐射之间的特殊关联完全是高剂量效应，而且寿命中期的辐射敏感性水平远低于两端。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/020b/1637879/3bd82da8562d/envhper00303-0044-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/020b/1637879/bf2451edcc38/envhper00303-0042-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/020b/1637879/38e318775f68/envhper00303-0042-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/020b/1637879/c727b607c58e/envhper00303-0043-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/020b/1637879/42220a1d5e6d/envhper00303-0043-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/020b/1637879/3bd82da8562d/envhper00303-0044-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/020b/1637879/bf2451edcc38/envhper00303-0042-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/020b/1637879/38e318775f68/envhper00303-0042-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/020b/1637879/c727b607c58e/envhper00303-0043-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/020b/1637879/42220a1d5e6d/envhper00303-0043-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/020b/1637879/3bd82da8562d/envhper00303-0044-a.jpg

相似文献

1
The role of epidemiology in the detection of harmful effects of radiation.流行病学在辐射有害效应检测中的作用。
Environ Health Perspect. 2000 Feb;108(2):93-6. doi: 10.1289/ehp.0010893.
2
A-bomb survivors: reassessment of the radiation hazard.原子弹幸存者：辐射危害的重新评估
Med Confl Surviv. 1999 Jan-Mar;15(1):47-56. doi: 10.1080/13623699908409424.
3
Absence of evidence for differences in the dose-response for cancer and non-cancer endpoints by acute injury status in the Japanese atomic-bomb survivors.在日本原子弹爆炸幸存者中，未发现癌症和非癌症终点的剂量反应因急性损伤状况而存在差异的证据。
Int J Radiat Biol. 2002 Nov;78(11):1001-10. doi: 10.1080/0955300021000013803.
4
Cancer and non-cancer effects in Japanese atomic bomb survivors.日本原子弹幸存者中的癌症及非癌症影响。
J Radiol Prot. 2009 Jun;29(2A):A43-59. doi: 10.1088/0952-4746/29/2A/S04. Epub 2009 May 19.
5
Age-time patterns for cancer and noncancer excess risks in the atomic bomb survivors.原子弹爆炸幸存者中癌症和非癌症超额风险的年龄-时间模式。
Radiat Res. 2000 Dec;154(6):733-4;discussion 734-5.
6
Epidemiological research on radiation-induced cancer in atomic bomb survivors.原子弹爆炸幸存者中辐射诱发癌症的流行病学研究。
J Radiat Res. 2016 Aug;57 Suppl 1(Suppl 1):i112-i117. doi: 10.1093/jrr/rrw005. Epub 2016 Mar 13.
7
[Health effects of atomic bomb radiation].[原子弹辐射对健康的影响]
Rinsho Byori. 1994 Apr;42(4):313-9.
8
Leukemia: lessons from the Japanese experience.白血病：来自日本经验的教训。
Stem Cells. 1997;15 Suppl 2:135-9. doi: 10.1002/stem.5530150720.
9
The observed relationship between the occurrence of acute radiation effects and leukemia mortality among A-bomb survivors.原子弹爆炸幸存者中急性辐射效应的发生与白血病死亡率之间的观察到的关系。
Radiat Res. 1991 Feb;125(2):206-13.
10
A-bomb data: detection of bias in the Life Span Study cohort.原子弹数据：寿命研究队列中偏差的检测
Environ Health Perspect. 1997 Dec;105 Suppl 6(Suppl 6):1519-21. doi: 10.1289/ehp.97105s61519.

引用本文的文献

1
Hospitalizations Among Chernobyl-Exposed Immigrants to the Negev of Israel, 1992-2017: A Historical Follow-Up Study.1992 - 2017年以色列内盖夫地区切尔诺贝利事故受影响移民的住院情况：一项历史性随访研究
J Immigr Minor Health. 2022 Apr;24(2):469-480. doi: 10.1007/s10903-021-01202-x. Epub 2021 May 11.
2
Blastopathies and microcephaly in a Chornobyl impacted region of Ukraine.乌克兰切尔诺贝利受影响地区的胚细胞病和小头畸形。
Congenit Anom (Kyoto). 2014 Aug;54(3):125-49. doi: 10.1111/cga.12051.
3
Objectivity and ethics in environmental health science.

本文引用的文献

1
Some features of leukaemia mortality.白血病死亡率的一些特征。
Br J Prev Soc Med. 1955 Apr;9(2):81-8. doi: 10.1136/jech.9.2.81.
2
STUDIES OF THE MORTALITY OF A-BOMB SURVIVORS. 3. DESCRIPTION OF THE SAMPLE AND MORTALITY, 1950--1960.原子弹爆炸幸存者死亡率研究。3. 样本描述与死亡率，1950 - 1960年
Radiat Res. 1965 May;25:25-52.
3
A survey of childhood malignancies.一项儿童恶性肿瘤调查。
环境卫生科学中的客观性与伦理道德
Environ Health Perspect. 2003 Nov;111(14):1809-18. doi: 10.1289/ehp.6200.
4
The risk linked to ionizing radiation: an alternative epidemiologic approach.与电离辐射相关的风险：一种替代的流行病学方法。
Environ Health Perspect. 2001 Sep;109(9):877-80. doi: 10.1289/ehp.01109877.
5
Re: "Collision of Evidence and Assumptions: TMI Déjà View".关于：“证据与假设的碰撞：三哩岛似曾相识景象”。
Environ Health Perspect. 2000 Dec;108(12):A547-A549. doi: 10.1289/ehp.108-a547.
6
Bisphenol A and Dental Sealants: Olea's Response.双酚A与牙科密封剂：油橄榄的应对措施。
Environ Health Perspect. 2000 Dec;108(12):A546. doi: 10.1289/ehp.108-a546a.
7
TCE Meta-Analyses: Wartenberg et al.'s Response.三氯乙烯荟萃分析：瓦尔滕贝格等人的回应。
Environ Health Perspect. 2000 Dec;108(12):A543-A544. doi: 10.1289/ehp.108-a543.
Br Med J. 1958 Jun 28;1(5086):1495-508. doi: 10.1136/bmj.1.5086.1495.
4
Detecting the health risks of radiation.检测辐射的健康风险。
Med Confl Surviv. 1999 Apr-Jun;15(2):138-48. doi: 10.1080/13623699908409448.
5
Effects of exposure to external ionizing radiation on cancer mortality in nuclear workers monitored for radiation at Rocketdyne/Atomics International.
Am J Ind Med. 1999 Jan;35(1):21-31. doi: 10.1002/(sici)1097-0274(199901)35:1<21::aid-ajim4>3.0.co;2-x.
6
Leukaemia and sudden death.白血病与猝死。
Leuk Res. 1998 Mar;22(3):289. doi: 10.1016/s0145-2126(97)00167-7.
7
Risk of childhood cancer from fetal irradiation.胎儿期受辐射导致儿童患癌的风险。
Br J Radiol. 1997 Feb;70:130-9. doi: 10.1259/bjr.70.830.9135438.
8
Reanalysis of Hanford data: 1944-1986 deaths.汉福德数据重新分析：1944年至1986年死亡情况
Am J Ind Med. 1993 Mar;23(3):371-89. doi: 10.1002/ajim.4700230302.
9
A-bomb survivors: further evidence of late effects of early deaths.原子弹爆炸幸存者：早期死亡后期影响的进一步证据。
Health Phys. 1993 May;64(5):467-72. doi: 10.1097/00004032-199305000-00002.
10
Childhood cancers and competing causes of death.儿童癌症与其他致死原因
Leuk Res. 1995 Feb;19(2):103-11. doi: 10.1016/0145-2126(94)00122-q.