Chan K O, Lim I J, Baladas H G, Tan W T
Division of Plastic Surgery, Department of Surgery, National University Hospital, Singapore.
Br J Plast Surg. 1999 Dec;52(8):665-7. doi: 10.1054/bjps.1999.3180.
Trichilemmal carcinoma is a rare skin tumour occurring in the sun-exposed areas of the elderly. It originates from the external root sheath of the hair follicle and is the malignant form of the trichilemmoma. Clinically, it may be mistaken for a squamous cell carcinoma, basal cell carcinoma, nodular melanoma or keratoacanthoma. It is distinct from the proliferating trichilemmal tumour. Trichilemmal carcinoma is usually a solitary lesion and an extensive literature search revealed no previously reported cases of multiple tumour presentation. We describe a case of trichilemmal carcinoma arising from three distinct sites in the same patient and discuss the differential diagnoses, histological features and probable aetiology of this rare tumour.
外毛根鞘癌是一种罕见的皮肤肿瘤，发生于老年人暴露于阳光下的部位。它起源于毛囊的外根鞘，是毛根鞘瘤的恶性形式。临床上，它可能被误诊为鳞状细胞癌、基底细胞癌、结节性黑素瘤或角化棘皮瘤。它与增生性毛根鞘瘤不同。外毛根鞘癌通常为单发病变，广泛的文献检索未发现先前报道的多发肿瘤病例。我们描述了一例同一患者三个不同部位发生外毛根鞘癌的病例，并讨论了这种罕见肿瘤的鉴别诊断、组织学特征及可能的病因。
