信号转导：细菌趋化作用中的“毛头小子”

Signal transduction: hair brains in bacterial chemotaxis.

作者信息

Stock J, Levit M

机构信息

Department of Molecular Biology, Princeton University, New Jersey 08544, USA.

出版信息

Curr Biol. 2000 Jan 13;10(1):R11-4. doi: 10.1016/s0960-9822(99)00248-1.

DOI:10.1016/s0960-9822(99)00248-1

PMID:10660286

Abstract

The conserved cytoplasmic domains of bacterial chemotaxis receptors are a fibrous arrangement of alpha-helical coiled coils that look a lot like hair. Such bundles of alpha-helical filaments mediate sensory-motor responses in all prokaryotic cells. How do they work? Very nearly perfectly is probably as good an answer as any.

摘要

细菌趋化性受体保守的胞质结构域是α-螺旋卷曲螺旋的纤维状排列，看起来很像毛发。这种α-螺旋丝束介导所有原核细胞中的感觉运动反应。它们是如何工作的呢？几乎完美可能是一个不错的答案。