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[肝泡型包虫病的外科治疗]

[Surgical treatment of hepatic alveolar echinococcosis].

作者信息

Heyd B, Weise L, Bettschart V, Gillet M

机构信息

Service de Chirurgie Digestive, Centre Hospitalier Régional et Universitaire (Direktor: Prof. Dr. G. Manciou) Besançon.

出版信息

Chirurg. 2000 Jan;71(1):16-20. doi: 10.1007/s001040051007.

DOI:10.1007/s001040051007
PMID:10662997
Abstract

INTRODUCTION

Alveolar hydatid disease is an uncommon parasitosis found in the northern hemisphere, caused by the larval stage of a tapeworm growing in the liver: Echinococcus multilocularis. It behaves like a malignant tumor, producing liver necrosis and invading the biliary tract, main vessels and surrounding structures.

METHODS

Review of the different therapeutic approaches in hepatic alveolar echinococcosis over 21 years in an epidemic area.

RESULTS

The various surgical approaches (all types of hepatectomy, palliative surgical procedures and liver transplantation) were combined with medical, endoscopic and radiological interventional treatment. Recently, asymptomatic forms were more frequently encountered.

CONCLUSIONS

The wide use of ultrasonography and specific serological tests have led to early diagnosis, allowing more curative hepatectomies.

摘要

引言

肺泡型包虫病是一种在北半球发现的罕见寄生虫病,由生长在肝脏中的绦虫幼虫阶段——多房棘球绦虫引起。它的行为类似于恶性肿瘤,会导致肝脏坏死并侵犯胆道、主要血管和周围结构。

方法

回顾一个流行地区21年来肝泡型包虫病的不同治疗方法。

结果

各种手术方法(各类肝切除术、姑息性手术和肝移植)与药物、内镜和放射介入治疗相结合。最近,无症状形式更为常见。

结论

超声检查和特异性血清学检测的广泛应用导致了早期诊断,从而使更多的根治性肝切除术成为可能。

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1
[Surgical treatment of hepatic alveolar echinococcosis].[肝泡型包虫病的外科治疗]
Chirurg. 2000 Jan;71(1):16-20. doi: 10.1007/s001040051007.
2
Comment on surgical approaches for definitive treatment of hepatic alveolar echinococcosis: results of a survey in 178 patients.评论肝泡型包虫病的确定性治疗手术方法:178 例患者的调查结果。
Parasitology. 2020 Nov;147(13):1408-1410. doi: 10.1017/S0031182020001390. Epub 2020 Aug 3.
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Current interventional strategy for the treatment of hepatic alveolar echinococcosis.肝泡型包虫病治疗的当前介入策略。
Expert Rev Anti Infect Ther. 2016 Dec;14(12):1179-1194. doi: 10.1080/14787210.2016.1240030. Epub 2016 Oct 8.
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[New imaging diagnostics of liver echinococcosis].[肝包虫病的新型影像诊断方法]
Wiad Parazytol. 2001;47(4):565-72.
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[Left hepatectomy for alveolar echinococcosis of the liver].
Sem Hop. 1971 Nov 20;47(46):2675-8.
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Liver Transplantation for Incurable Alveolar Echinococcosis: An Analysis of Patients Hospitalized in Department of Tropical and Parasitic Diseases in Gdynia.不可治愈性肺泡型肝包虫病的肝移植:格但斯克热带与寄生虫病科住院患者分析
Transplant Proc. 2016 Jun;48(5):1708-12. doi: 10.1016/j.transproceed.2016.01.087.
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[Hepatic alveolar echinococcosis: a rare cause of recurrent, surgically curable abdominal pain in children].[肝泡型包虫病:儿童反复出现且可通过手术治愈的腹痛的罕见病因]
Arch Pediatr. 2012 Nov;19(11):1200-4. doi: 10.1016/j.arcped.2012.08.013. Epub 2012 Oct 18.
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[Echinococcus multilocularis causing extensive biliary obstruction (author's transl)].多房棘球绦虫导致广泛的胆道梗阻(作者译)
Rofo. 1975 Mar;122(3):242-4. doi: 10.1055/s-0029-1230063.
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Is alveolar hydatid disease of the liver incurable?肝脏肺泡状棘球蚴病无法治愈吗?
Ann Surg. 1980 Jul;192(1):118-23. doi: 10.1097/00000658-198007000-00021.
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Hepatic alveolar echinococcosis: clinical and radiologic features and endoscopic management.肝泡型包虫病:临床、影像学特征及内镜治疗
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引用本文的文献

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Risk factors and a simple model for predicting bile leakage after radical hepatectomy in patients with hepatic alveolar echinococcosis.肝泡型包虫病患者根治性肝切除术后胆漏的危险因素及预测简易模型
Medicine (Baltimore). 2017 Nov;96(46):e8774. doi: 10.1097/MD.0000000000008774.
2
Proposal of an ultrasonographic classification for hepatic alveolar echinococcosis: Echinococcosis multilocularis Ulm classification-ultrasound.肝泡型包虫病超声分类的建议:多房棘球绦虫乌尔姆分类-超声
World J Gastroenterol. 2015 Nov 21;21(43):12392-402. doi: 10.3748/wjg.v21.i43.12392.
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Hepatobiliary complications of alveolar echinococcosis: A long-term follow-up study.
肺泡型肝包虫病的肝胆并发症:一项长期随访研究。
World J Gastroenterol. 2015 Apr 28;21(16):4925-32. doi: 10.3748/wjg.v21.i16.4925.
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Effects of in vitro exposure of Echinococcus multilocularis metacestodes to cytostatic drugs on in vivo growth and proliferation of the parasite.体外暴露于细粒棘球蚴原头节的细胞毒性药物对寄生虫体内生长和增殖的影响。
Parasitol Res. 2010 Jul;107(2):459-63. doi: 10.1007/s00436-010-1892-0. Epub 2010 May 12.