经产妇妊娠晚期的眼压降低作用高于初产妇。

The ocular hypotensive effect of late pregnancy is higher in multigravidae than in primigravidae.

作者信息

Qureshi I A, Xi X R, Yaqob T

机构信息

Department of Biochemistry, Rawalpindi Medical College, Rawalpindi, Pakistan.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2000 Jan;238(1):64-7. doi: 10.1007/s004170050011.

DOI:10.1007/s004170050011

PMID:10664055

Abstract

BACKGROUND

Systemic hypertension and degenerative vascular disease are more common in multigravidae than in primigravidae. The present study investigated whether the known ocular hypotensive effect of late pregnancy is influenced by the number of pregnancies.

METHODS

Intraocular pressure (IOP) was measured in normotensive third-trimester primigravidae and multigravidae along with nulligravida controls by means of the Goldmann applanation tonometer. Depending upon the number of previous pregnancies, multigravidae were divided into four subgroups.

RESULTS

The IOP of the pregnant group (primigravidae and multigravidae together) was (mean+/-SEM) 2. 1+/-0.07 mmHg (P<0.001) lower than in the nulligravida control group. The IOP of nulligravidae was 1.7+/-0.06 mmHg (P<0.001) and 2.5+/-0. 01 mmHg (P<0.001) higher than in third-trimester primigravidae and multigravidae, respectively. In all subgroups of multigravidae IOP was significantly lower (P<0.02) than in primigravidae. The differences among different subgroups of multigravidae were statistically insignificant.

CONCLUSIONS

Gravidity influences IOP and should be taken into account in future research.

摘要

背景

与初产妇相比，经产妇中系统性高血压和退行性血管疾病更为常见。本研究调查了晚期妊娠已知的眼压降低效应是否受妊娠次数影响。

方法

通过Goldmann压平眼压计，对血压正常的晚期妊娠初产妇、经产妇以及未孕对照者测量眼压。根据既往妊娠次数，将经产妇分为四个亚组。

结果

妊娠组（初产妇和经产妇合并）的眼压（平均值±标准误）比未孕对照组低2.1±0.07 mmHg（P<0.001）。未孕者的眼压分别比晚期妊娠初产妇和经产妇高1.7±0.06 mmHg（P<0.001）和2.5±0.01 mmHg（P<0.001）。在经产妇的所有亚组中，眼压均显著低于初产妇（P<0.02）。经产妇不同亚组之间的差异无统计学意义。