Qureshi I A
Department of Physiology, Rawalpindi Medical College, Rawalpindi, Pakistan. Physiology Department, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi, Pakistan.
Chin Med Sci J. 1997 Mar;12(1):53-6.
Decrease in intraocular pressure (IOP) during pregnancy has been reported by previous studies, but amount of decrease varies from study to study. Moreover, previous studies have concentrated on the last trimester of pregnancy or one reading per trimester. IOP changes throughout the pregnancy have never been described. Therefore, the present study was planned to determine IOP throughout the pregnancy, after placing control on IOP affecting factors.
Thirty-six pregnant and same numbers of non-pregnant women of the same age group were studied. IOP measurements were taken at four week intervals throughout the pregnancy, with the Goldmann applanation tonometer.
As compared to control subjects, up to 8th week, IOP remained the same. At 12th week, it becomes significantly lower. The IOP differences between first and second (P < 0.05), and second and third (P < 0.001) trimesters of pregnancy were significant. In every subject, IOP decreased during pregnancy. However, there were variations among individuals in the extent of IOP decrease.
With advancing pregnancy, intraocular pressure decreases. Knowledge of the normal level of intraocular pressure in various stages of pregnancy may help glaucoma screeners.
先前的研究报道了孕期眼压（IOP）会降低，但降低的幅度因研究而异。此外，先前的研究集中在妊娠晚期或每三个月进行一次读数。从未描述过整个孕期眼压的变化情况。因此，本研究旨在在控制眼压影响因素后，确定整个孕期的眼压。
研究了36名孕妇和相同数量的同年龄组非孕妇。在整个孕期，每隔4周用戈德曼压平眼压计测量眼压。
与对照组相比，直至第8周，眼压保持不变。在第12周时，眼压显著降低。妊娠第一和第二孕期（P < 0.05）以及第二和第三孕期（P < 0.001）之间的眼压差异显著。在每个受试者中，孕期眼压均降低。然而，个体之间眼压降低的程度存在差异。
随着孕期进展，眼压降低。了解孕期各阶段眼压的正常水平可能有助于青光眼筛查人员。
